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This document contains clinical reports from July and August 1954 detailing tests involving sodium amytal and benzedrine administered intravenously and orally to subjects, with one subject experiencing amnesia regarding conversations held under medication.

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Tran~mitted herewiLh 3rc the clinicn' r~nort!' of te~.·.s c·mJur::tf':'d·'during ; . Julv and ,\ugu~t 195<1. Tht> outside tcn1!-'('T'Iture was v:rory hir.h with a r,.:n st:"ln!ly humid .;d.mosph~re. Te!.lt!l were c·mrlucteci in n~m-."1.1r conrlition:-·1 btt1hbnf~~ and .!stin1atctl m-; de tcn':'er.~tur·~.:; r:-~ng(~d ft·on1 r')q to 1')1) d~Rt:(:<.:!_; F. Test Hl •·· .':..,.. Thl! drug US(!d in this cas~ wa.s sodium amytal intravenously, SYo solution at tho;: rate 1>f 1 cc a minute. The stlmul.:mt employed was br-?nzedl'inc ;nlra vancously at th<:! r:tte of 1 cc a minute plus 10 mg giv~n orallr at the completitlll o£ the t.cchni•lue. . Th.: intravcno':ls injection was b~gun at 133;~. ,\l 134,!, 'J. •I cc hau been adminislereJ. At 1345 the Subject was sound asleep. ll was po!lsible to arouse him but in order to obtain the exact state desired intravenous benzP.drine, as a stimulant, was administered. At 1405, he wa! accessible, but his spct:ch was quite thick. At that time 1 cc more of b~nzeririne wu.~; given intravenously fol lowing which he w:ts in the prorer state for the interrog01tion. The interrogation and other conv:!rs:ltion \Vas continu~d unlil 1449 wh'"n the Subject W:tB ~hi tor. • to sleer, wh1ch he did. At 1453, he wa.s giv~n Z cc of th·! benz~drine soluLion, follow ng which h\! becC\me quite wide awnke. At 1615, 1 benzet.ir1ne tablet was given to be taken orally, th~ dose being 10. mg. The Subject had amnesia as to his conversntidns under the influence r.1f the medication. Thi~ test ·.vas rcgard·~d as successful. ' Th~ drug used in this case was sodium amyte1l intr01venously, 5o/o solut1on given at the rate of 1 cc: a minute, The total amount administered was 16 cc or '1. 8 gm. The stimulant wns benzedrinet 2.0 mgt 2-5 cc intrav::!nously. A total of 9 cc was given or 36 m~. The ;njt~ction was started :tt 1141. At l15Z., after the ar.lministri'\tion of ll cc of sodium amytal 9<.'lution, the Subject said his head felt wooz·)·· =At 1155, he was nearly asleep but :\wakened with a ,;tarl upon bein·~ arou5ed. Frnm th,1.t tlme on, he ....· ar. occ;,!;1on:11ly given 1 cc mor~ of the solution in order to m:1.\nbtin the prop\!r state for the technir1uc. l\.t 12Yl, he was ag:un asleep but easily aroused and the sarn~ at 12.45. The desir~d df~ct of fh~ m~·.licnbon was ohrain~':i. Th•: .Subj~~ct. w.":'.S inter- r(•gated •mde:- !l;muhte·l -en<:n"l'/ con•lilions an~ h.:! The image prominently features a visually striking blue and silver graphic of a bank vault door on the left side, symbolizing security and access to hidden information. To the right of the vault graphic, stylized white text in a slightly distressed font reads "THE BLACK VAULT." Below this title, a block of white text provides information about the document's origin: it's from "The Black Vault," an online database of declassified government documents, specifically from the "MKULTRA/Mind Control Collection," containing over 20,000 declassified pages from the CIA. The text further states the collection is free to download and provides a URL: "http://mkultra.theblackvault.com." The overall impression is that of a gateway to sensitive, historical information. This document is a typed report with handwritten annotations, primarily numerical time stamps and occasional short phrases. There are no photographs, diagrams, tables, stamps, or forms present. The content is divided into two "Test" sections, each detailing a medical experiment. The handwritten additions appear as marginalia and add further detail to the typed text, suggesting interjections or observations during the recording of the experiment. There are no redactions or obscured content. given 1 cc mor~ of the solution in order to m:1.\nbtin the prop\!r state for the technir1uc. l\.t 12Yl, he was ag:un asleep but easily aroused and the sarn~ at 12.45. The desir~d df~ct of fh~ m~·.licnbon was ohrain~':i. Th•: .Subj~~ct. w.":'.S inter- r(•gated •mde:- !l;muhte·l -en<:n"l'/ con•lilions an~ h.:! •.:.ras 'l'tit~ vinlcnt. U['On occas,cns dur\n~ th'! interroca.Uon ash~ wns cnnvl!lce~l th1t th~ :nlcrrop.""tttH5 wl".r-•: his rnemi~!l. /\t ll.SO, t.h~ stimul:tnt -.•:as bc~11n and alth~m:;h h~ graduall-; aw;d~·:Iv.:d, at 1Z.5r~, ~Her the :.\dm n1slraliun ('{ 7cc of bt!n7,;-:rlrin·! S0l11ttrm, he~ s<~i<.l thal h. stJll fell sleepy. llc wa3 J_pvcn 2cc mor~ <~.l 131)3. At 1353, he w<Ls awake. t\t 11'14, he wa~ sent to eat anl.i then sleep. He sa:d he still fell a httlc dizzy. r. --------------------------------------··-- -·-·--·· . ...... ·- ........ .. .. -- . . .. .. ........ _..:. ..: -- .. · ... ~ .,.. -"·~· ·, .... ,._: .•••..· ~· -· •. ~·Jj·".·~~-- . --:· \:. ' o · :.: - .. ·...•. ·-·- '. ~--- ~ ~· T h ... Sub j e c t h :1. d a m n" s i :t a 3 t ,., hi <; c r> n ·: c r s ;1 t i o·n .;; u n de r l h ~~ i nfl u c n c t: o f tIt c tn·~di C:llion. Th! !-. t,:~t wa~ rrg.~ rd ;:u as succ::: ~ sful. The medication ndm1nistert-d wns sodium amyla1 intr.avenou~ly, S'lo .....: . ' solution g•.v·~n al the rale of l cc a minute. The otimulantu were bcnz1=r.lrinc in trav~n•.:uslr and p.icrotox:in inlrnv~nous1y. The toLt1 amount of sodium arnyt3.1 adminlstrcr~d w~ts 16 rc nr () .. B gm. Th~ ::l.tnount of the benzedrine s ··lu 1on t.otalecl 5 cc or .?.:) mr; was given :1.nu 1. 5 cc of picrot.ox\n. The mt:dicalion was begun at 1048. At. 1106, after 11 cc had b.:en admin is.tercrl, Lhe Subjecl cornplnined of blurred vision. Al 111.2, follClwma lh~ .admin istratir>n r>f 1~ cc (total). his ·:y·~s r-;r:cmed heavy • .i\t llZl, u.ftcr the total :Lri ministration of 16 cc, he \V<l.S found l.o be yawni11g. .:\t llZ?, be w:ts aslcr:i' but co~1ld be f~irly e.1.s!ly "l.rouncd ..\ t lZlZ, the d•.!Sir~d dfcct of the mr>di~tiun was obti\incd :1.n·l at 12.15 sur:ce5 !"ful interrr>gation was beg on. At 124 7, the stinmlant Wi\! b·!gun, th<tt is, benzedrine intra_venously. The image is a typewritten document, likely a report or log, detailing tests and observations. There are no photographs, stamps, or handwriting present. However, there are several instances of the document's text being obscured by black redactions, particularly in the right margin and near the bottom of the page. The content appears to be a chronological account of medication administration and the subject's responses, with specific times and dosages noted, suggesting an experimental or observational setting. 16 cc, he \V<l.S found l.o be yawni11g. .:\t llZ?, be w:ts aslcr:i' but co~1ld be f~irly e.1.s!ly "l.rouncd ..\ t lZlZ, the d•.!Sir~d dfcct of the mr>di~tiun was obti\incd :1.n·l at 12.15 sur:ce5 !"ful interrr>gation was beg on. At 124 7, the stinmlant Wi\! b·!gun, th<tt is, benzedrine intra_venously. At 125;:, a total. of 5 ~.:c had been _, administered and e~.lthougl:l the Subject could be aro\\s·::d, he still seemed quite . •, slee !:')'. At 12.21, pic rotoxj.n was given, a total of 1.: 5 cc. At 1 ZZ6, th~ Subject was =\Wi\k.~. However, in the' afternoon ~iter having ~ud (lis lunch, he .,,.,as vis itcd in h:s rrlom .1t 1445 and w;1s found to be sleeping ooundly. I"h-; Snbicct h::\r.l :unnes1:1 ~.s t':l his convers~tionr.; nnJ:::r th~ 1n£lucnce o( th~ medic:ltton. This test w<ts regarded as successful. • • Test H4 =-- The medication in this ca$ ~ wa :o; sodium amy tal int rav,cnousl y, S~o Sl')luti on administered at the rule of l cc a minute. The total amount of sodium amyta.l was 15 cc: t")r ·). 75 gm.: The stin1ulants were picrotoxin intravenous!}'• total Z cc and bcnzccll'in<!. 1 ') m::; orally. • • The :ntravenous s,,dium a.mytal was started at 151.4 with 7 cc belnf. given a!. the r~tc of 1 cc n minute <~.nd th.;;n :1. L~w minutes were <'lllow~d to elaps<! to observe th~ effect followinr whtch 2. more cc were given. A waiting p~riod again followed wlth 3 more cc b~in:;!' s;ivcn <1nd then ng:\i.n awn it.ing jH~riod followed by 3 mor.~ cc and f;n:tlly 3 cc 3t 1604. The irt. .ermitt~nt nt\ture W:t!J to hecq !he p:lticnt at the prop~!' :1~inl forth~ int~rrog1.t.ion. ,\t 1610, th~ :'l•lmin•3tr::tti('ln of 2.. 5 cc of picrotoxin l11d b-=~n comt.lld-:=d. TlH~ Subject ~till s1e['t f ~uowing t.his by pcrmis:.ion for 5 min u t. c s . H c w a s then "'._.,. :l. ken c d. At l 7 () 1, l. 5 c c o £ pic r 0 to"< ; n \V .1. s ad m in - lstered :J.nrl :lt 17~15,· 0. 5 cc of picrotoxin. The Subject, c.1t that time, w~'3 a.wa.kc but said that he felt sleepy.: At 172.0, 10 mg of oral benzedrine was given. : - 1> - ~· . . •. . ~""' ··-~ ;i' .... ...... _ ••• • ~-!'>'-:'·~- .1"".. .~ This page contains typed text, appearing to be a report or log, with handwritten annotations and some faint markings that could be stamps or pre-printed elements. There are no photographs, diagrams, or forms with filled-in fields. The text discusses medical procedures, specifically the use of sodium pentothal and benzedrine, and their effects on a subject, including amnesia. There are no visible redactions or obscured content; the page is entirely legible. The visual content primarily consists of the typed report itself, with some minimal extraneous marks. :J.nrl :lt 17~15,· 0. 5 cc of picrotoxin. The Subject, c.1t that time, w~'3 a.wa.kc but said that he felt sleepy.: At 172.0, 10 mg of oral benzedrine was given. : - 1> - ~· . . •. . ~""' ··-~ ;i' .... ...... _ ••• • ~-!'>'-:'·~- .1"".. .~ ' •• ~"':_~. .... ~-·-~---~-~-· ..... , .... ,. .... • •• ,~·.·-~ •• ~. ..... - .. -. -~·. ... -1 ............ ·~ ...... . . ·•. .•• • : .-. • •• '!' ., . •• •• •• • •• .J> ·--~ :• .... . ,: . I ,. :. . 1 The Subject Jn-:i ~m~1~~\a as to h\:; conv~rsalions under the in!luenc::: o£ the 0 me-:Hcati'.:ln. This test wJ. s rcga rdcd a~ ~ •'Ccc.s dul. Test ff5 - The dru~ us~d in this case was sodium penihothal. A 2. l/2.'fo solution was given intravt:nou~ly. The !trst. 10 cc was gi.vcn at the rate u{ t cc a mlnut.!; beyond that., 1 cc ~1. minute. ThL~ st1mulant was benzet.lrint:, 10 mB or<~.lly. The tol-::tl amount of ~uJi.um p~titholha.l was 19 cc rJ! the solution which would r"!pn'!>t!nt nol quilt. '.). 5 gm. o£ the urug. T~ :ntravcnous sodium n:nlhoth.:tl was sl.lrted at lll)!l •.\ t 1115, l·J cc had b+.!en admmistcred. At 1107, the injection was aga1n started and t.his con tinued at 1111, 4 more ce havi.n~ been administered. At that tlme, the Subject dcrncd off but was easily aro11s::d. At 1117. the inj~ct1on was .;.g.:tin started and this continued after tht~ .tuminislration of 1 more cc. Th: s r·rocedu\·~ o1 ~;tvJag 1 cc intermittently was rce~<l.tcd C.\1 112.2, 1125, 113·) <LnJ 113,1. rh~ Or\gi.ni11 :·ian was to RIVC a.n inlra.v~nous ~till"~lll:l.nt biJt th-e ne\!dle h~d bcc•:me clop~cd due h <'.blood clot therein and it. W?..S believed t'.:l be in<~.rivisabl~ to have to make another puncture, hence, the stimulant was giv~n orally at l2.ll { 11'! mJl of ben.7.cdrin~). .\t 12.35, bh.ck coffe~ was l\drn\nist~red. · Th~ Suhj•:::r.t was then instruc-ted to rest for a hn.H of an hour anu then eal his midtld.y meal. The tnc,lic='.tion -.-.~s eff::clive .::1s to the Jee;ircc.l rcuu1ts. It. is bd.ievcd t.h,t : wh.~n thil' ~<;rli.c:ubr rlrng, sodium p~nt')th~l. 1.s u::·~d. lhc mcLhod employed ll1 thi!l <..:J.~~ ts b::!!t, tl1:1l !!'>, aft.~r tl1c miti."ll st:t~e nf iTnp,""tire•l con!;c-;ousne.sr; b~ produced, it is adv•so.bl~ t~ give intermitt~nlly smt=~ll amount-:~ u! th-: tnc,lic='.tion -.-.~s eff::clive .::1s to the Jee;ircc.l rcuu1ts. It. is bd.ievcd t.h,t : wh.~n thil' ~<;rli.c:ubr rlrng, sodium p~nt')th~l. 1.s u::·~d. lhc mcLhod employed ll1 thi!l <..:J.~~ ts b::!!t, tl1:1l !!'>, aft.~r tl1c miti."ll st:t~e nf iTnp,""tire•l con!;c-;ousne.sr; b~ produced, it is adv•so.bl~ t~ give intermitt~nlly smt=~ll amount-:~ u! th-: drur.; in .... order to mainta:n the desired state. Vlhen using ~·,dium ~mytal, however, due to the more prolonged eff\!ct, it is not so nece~sary to i.nt.~r-.s!'ace minute doses \n this w?..y. The advantafe of sodium pentothal is that it i3 much easier to h<~.ve 1... the 1nan back in h,s ll;Orm:J.l state in ;1. cumpa r<lti vdy short tllne but it is nrJt ' cerL:11n that the a.mncs:a will be as dcfin;te as in the us~ of thP. longer act.inr, cll·ug . ; ··. In th~!.i rl-lrt<cul-tr cas~. ;}.tnne5Ia for the int:!rrogation W"!S prorlucl!d. ;\.lgo sodnun ~ , :. ,:. · . . penthoth::~.l i.:o sl•gl;tly mor'!! dangerous th?..n sndinm <nn:;tal in the mor•! r'I:.'i.d pro ~. ductinn rJf reseiralory 1a.lur~. ·, j ~;~· · ·rl,c Subj·.~ct hali. an1n-~sia. n:; to l1ir, c:nnv~rsClti(ltlS UJl~"jer tltt~ ;.n.!lllCllCC o£ tl1c medic:;d.ion. Thi:: test -vas regarded a:.; .!l11Ct:e:Jdul. Sudimn Fi.!ntat.:hal, .intravenously, wns u3ecl in this case, .! l/2/'o sulution at the rai.e of 1" cc a minule.= The total amount of sodium pentothu.l W.iS '/. ·1 cc ........ of the solution, repres~nting a;;,proximately 0. 2.4 gm of tht! drug. The &timulant was intravenous coramine • ..... .. c.. ·-..~-· .- •· ......- . .... ... - ~ -- "J •• --·. ·- -·

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