Doc 0000151819

. _-\- ~r.O) iJJ.. ,._ I I, ....,- . PREL IMlNARY REPORT ON 302 r~- The material furnished was kept in a desiccator in a cool room until required. Appropriate doses w.ere suspended in distilled water and adMinistered orally •. Subjects were former morphine addicts, many of them experienced with LSD. ~aterial was administered with the patients fasting at 8 a;m. The measurements included body temperature, recumbent and standina pulse rate, recumbent and standing blood pressures, p~pillary size, and threshold for kneejer~s. The pat1ents wer~ questioned once hourly concerning any subjective sensations they might have experienced, with particular emphasis being placed on illusions and hallucinations. One or two were tested at a time and tests ,.vere pa~ients done at intervals of a week. The dose was increased in a stepwise fashion becinning with 0.5 gram and lncre.asing to 2.5 a.rams. With the larger doses, 1.5 to 2.5 grams, we have consistently observed pupillary dilatation and inconsistently decrease in the threshold for kneejerk and a slight increase in blood pressure. No untoward toxic effects have developed. -- Page 2 Th2 subjective sensations reported to d~te have been disappointing. T\vO patients who have received 2 grams of the materials denied any subjectiv? experiences of any sort, other than slight aastric discomfort after inJestion of the drug. The patients receiving the 2.$-grarn dose reported slight nervousness, irritability at noise and other minor changes (these patients are known to be sensitive to 1 mcgfll./kg. of LSD). No gross changes in overt behavior have been observed. Only 4 grams of the material are still on hand. We feel that we should increase the dose even more than we have, and that also we should have some of the c.rude material as a reference standard·. 4 February 1958 /)'2( The image displays a stylized graphic of a vault door, rendered in shades of gray and blue, against a dark background. To the right of the vault, white text is overlayed on the dark background. The text states that the document was obtained from "The Black Vault," an online database of declassified government documents, specifically mentioning the "MKULTRA/Mind Control Collection." The text further indicates that this collection contains over 20,000 declassified pages from the Central Intelligence Agency (CIA) and provides a URL for downloading the entire collection. The URL is presented in a yellow font. The document is a declassified report page with typed text and handwritten annotations. The text describes a preliminary report on "K-302," detailing experimental procedures involving patients and substance administration. Handwritten annotations at the top right corner include "1.27" and "N-(6)(3)" with "file" beneath it. A numerical annotation "B-22" is present at the bottom right, likely indicating a page or document number. There are no photographs, diagrams, stamps, or obvious redactions visible on this page. The page is a typed document with a printed page number "Page 2" at the top right. There are two circular black ink blotches near the top center and top left. A horizontal line is visible at the top right, suggesting a staple or clip had been present. In the bottom left corner, "4 February 1958" is typed. Handwritten marginalia appears on the right side, reading "B-21" with some faint lines and dots underneath it. There is no visual evidence of experimental procedures, equipment, facilities, photographs, forms, diagrams, tables, or redactions.