Doc 0000151825
CIA
This document, from the CIA MKUltra mind-control program collection, contains a table comparing the potencies of LSD congeners in inducing psychoses and blocking serotonin-induced smooth muscle contraction.
This is one record. The archive holds the rest — ask it anything across the MKUltra files and every answer is cited to the page.
Ask the archive about this →a --- COMPARISON Or THE POTENCIES OF CONGENERS OF LSD IN INDUCING PSYCHOSES WITH POTENCIES IN BLOCKING SEROTONIN INDUCED CONTRACTION IN SMOOTH MUSCLE ANTISEROTONIN PSYCHOTOMIMETIC DRUG POTENCY I POTENCY 2 d·OIETHYLAMIDE OF LYSERGIC ACID (LSD) 100 100 A. ISOMERS L·DIETHYLAMIDE (L--LSDl 0.06 <0.025 d·ISO--DIETHYLAMIDE (lLD) 0.12 <2.0 B. DISUBSTITUTED. AMIDES d·l.YSERGIC ACID AMIDE ( l.A Ill) 4 <.3.0 d· LYSERGIC ACID DIETHYLAMIQE (DAM} 23 13 C. MONOSUBSTITUTED AMIOES d·MONOMETHYL. AMIDE 6 <5 ' d·MONOETHYL. AMIDE (l.AE) 12 5 C. CYCLIC AMIOES d· MORPHOLIDE ( L.SM l 2.0 10 d- PYROLL.IDIO (l.PD) 5.0 6 E. REMOVAL 0 F ACt 0 AMIDE -d·-LY-S-E-R-G-IC- -A-C-ID- ------------------ <I <3.0 F. RING-SUBSTITUTED DERIVATIVES (l) ON INDOLE NITROGEN I-ACETYL LSD (ALO) 210 >100 I· METHYL LSD ( ML.Ol 368 33 (2) ON CARBON 2 2-BROM-LSD CBOL.) 103 <0.5 . (3) ON INDOLE NITROGEN AND CARBON 2 l-METHYL-2· BROM LSD (MBL.l 533 <0.5 (4} ON INDOLE NITROGEN AND VARIATION IN ACID AMIDE I· METHYL· MONOETHYL AMIDE (MLAl II 1- ACETYL· MONO ETHYL AMIDE (ALA) II 1-METHYL-PYROLL.ADID (MPD) 5 1 • FROM DATA OF CERLETTI AND OOEPFNER, J.P.E.T. 122:124-136 (JAN.) 1958 2. EXPRESSED AS RATIO ; POTENCY OF LSD (I MCG/KG) X IOO POTENCY OF CONGENER 1]-3 I
The image displays a graphic representation of a vault door, a common symbol associated with secure storage and declassified information. Text overlaid on the graphic indicates that the document was obtained from "The Black Vault," an online repository of declassified government documents, specifically relating to the MKULTRA/Mind Control Collection. This collection comprises over 20,000 declassified pages from the Central Intelligence Agency (CIA) and is available for free download online. The presence of the vault imagery and the textual information suggest that the document is part of a significant release of sensitive historical information, emphasizing the security and secrecy surrounding its original content.
This page contains a table presenting chemical compounds and their potencies in blocking serotonin and causing psychotomimetic effects. There is handwritten annotation "133" in a circle at the top right, and another handwritten note "B-37" at the bottom right. The table includes columns for "DRUG", "ANTISEROTONIN POTENCY¹", and "PSYCHOTOMIMETIC POTENCY²". The drugs listed are various derivatives of lysergic acid diethylamide (LSD). Footnotes refer to data sources and calculation methods in small print at the bottom. There are no images of people, locations, equipment, or facilities visible on this page.
Original source: view the released document