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This memorandum for the file from June 1966 discusses a project proposal, suggesting a research progression from dogs to rhesus monkeys and then chimpanzees for electro-anesthesia studies, with eventual application to human volunteers or psychiatric patients.

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The image displays a digital representation of a document's header. On the left, a portion of a vault door is visible, rendered in a metallic gray with prominent circular mechanisms and levers, accented by a bright blue glow. To the right of the vault, the text "THE BLACK VAULT" is presented in a stylized, handwritten font with a dark blue gradient. Below this, white text explains that the document originates from "The Black Vault," an online database of declassified government documents, specifically mentioning the "MKULTRA/Mind Control Collection" and providing a URL for access. There are no photographs, handwritten annotations, stamps, forms, tables, redactions, or visual evidence of experimental procedures. ·~·· - "- 13 June 1966 !>lEMORANDUM FOR FILE SUBJECT: Project Proposal by Dr. 1. The basic research concept is well planned; however, the following sug gestione come to mind: a. I do not rec~~nd the exclusive use of dogs--actually 1,100 in number. During the past 5 years, there has been considerable research on electro anesthesia in the U.S. with animals of all kinds. In spite of this effort, lit tle is applicable to electro-anesthesia in the human. Preliminary investigations might well begin with the dog in order ~. to develop technics peculiar to inducing electro-anesthesia and in monitoring the condition of the animal during and after passage of electrical currents. c. Following the use of a reasonable number of dogs--perhaps 100--the research should be directed to the rhesus monkey.where the subject can be used repeatedly day after day. d. As soon as expedient, the observations should be transferred to a few chimpanzees, which, like monkeys, can be used repeatedly, varying the electrode placement and nature of the electric currents with continuous monitor- Of ing the an~ . ~ ~ ~~ly, . concurrently .with observations on the chimpanzee, human · ~ · ~S'\may be paid volunteers or perhaps patients in a psychiatric ward of a hospitan. 2. Comments re numbered paragraphs in proposal are as follcnnt: a. i.A. - I do not think it necessary to study all possible variations of electrical currents. The most promising values of frequency and intensity should be followed up as suggested by the present observations and published ~esults of other investigators in this field. b. "]:.B. - Placement of electrodes· may be very important and certaL-.ly · will differ the species of animal. The intensity of the currents will vary ~~th probably with animals speciea. c. II. - General anesthesia \rould be more important than local effects. Again it should not be necessary to perform major surgery in order to ascertain o the extent of the anesthesia induced. kby should drugs and not be used in 2 the studies with dogs? ·. -:. <~;, ·_. ,~~_fJ..·:~~~:.~ . _~g~;~.~f.~t~;_·:-.i:I,~_;:·.::;·~.---~-- .. . . . · : ~ :(., . .-.--,.··:~;~.·. ..._ :~ .~.: ~.:.._·~-~. . :_· .!._=·-_.~. ~- . x.-· · ·- :_ __ . > ,....., ... , .;-.~ .. . • . # .. ; ; .· . .•· : - - .¥- - .. - ." i " J' f ;! ~ _ This document is a typed memorandum with handwritten annotations in the margins. The handwritten portions appear to be comments or corrections related to the typed text. Visible handwritten marks include a scribble near the bottom left, and a checkmark-like symbol at the top left. There is also a circled number, "243", in the bottom right corner, possibly a document identifier or page number. The text discusses a research proposal involving electro-anesthesia and animal subjects. There are no photographs, diagrams, forms, stamps, or redacted content present on the page. ~ :(., . .-.--,.··:~;~.·. ..._ :~ .~.: ~.:.._·~-~. . :_· .!._=·-_.~. ~- . x.-· · ·- :_ __ . > ,....., ... , .;-.~ .. . • . # .. ; ; .· . .•· : - - .¥- - .. - ." i " J' f ;! ~ _ . ;: . ~ ,.: ' . . : i . / f " ! .' 4 . ' ". ~ / - F ~ ~ ~ ' . · i . , t · . • . . · . ~ I · ~ /' ~ '- / 7 ..I. - } .I. ~ . ~ ~. - C • ~ ", . 7 < • ';w - . ·. , ; . ~ .- . · ; -• . . - . . : . · ~ . ( · ~ , ·' ' ,.; · .• · • - ' _ . ~ ,.._ - ; . ·.< ~ . · . - - - ~· . - · :, - .. . ,.. ~ • .: - • \ : . . ~ . . ~ · · : . - · . : · · . .. · • ·'•., • : . .• . : .. · . :.. . • · . ~ . - . . . . : · . · .. • - . . ... . . ; ..: ·..:· ..... . ·~· . -• . ·. - · ' : : • ~-· • ) • , •. , r . · ._· . . < • :_ • • .. · . ; ·~ . .- . .. 13 'W • June . ~ . 1 96 • ~ 6 · • ~ . ' . . . : . · . • t .- : - < ~ . :- :r- - ..., .., ..... :-.· ... ___4 ....•... l,l./-l-.i.f;t~,. ,.... ;:;:-:.~ ~i.~.4~ ~..~ ·~'··i .'..~.._...f ,' J.h .; . . .· . - . .. . - . . -· - - . -. L ·. . . . _._,.:~~ . ~. . '· .--.·. . ~:.~··- . :.~M .. ·/~~ . . -~. . t . .. -~ ·, . . . _n J .. - ... .... .;.:; , .. ~-·::.· ~: ~ :L - ·. ... ~ , -.t : . .- This document is a typed report with a heavy texture of age and possibly water damage. It includes official stamps at the top right indicating the date "13 June 1966". There are no photographs, diagrams, or handwritten annotations visible. However, the document does contain several blacked-out or redacted areas, obscuring portions of the text, particularly within the numbered points of the report. The overall appearance suggests a historical document that has undergone declassification processes, with some content still concealed. ·. . . . _._,.:~~ . ~. . 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' - ', · ..;.-...•ot.r"!'';:r::')i ·. : t ·- : - ; ~~ .:·IV~-~:; lmPla.ii'tation of six chronfe ·electrodes within· the brzlin ·to ... ,_ :electriC. curr_ent·.-· etc~ may well influence· tho .curren~ ~is_t_ributioa. .;~.~;·. :. . -.~~..t....b.o.. . bra1D; 1'_-;-h.~ps.~~l.s. eou~~ .~e used_.for these.stud~!!s• . " . . . ' - ', · ..;.-...•ot.r"!'';:r::')i ·. : t ·- : - ; ~~ .:·IV~-~:; lmPla.ii'tation of six chronfe ·electrodes within· the brzlin ·to ... ,_ :electriC. curr_ent·.-· etc~ may well influence· tho .curren~ ~is_t_ributioa. .;~.~;·. :. . -.~~..t....b.o.. . bra1D; 1'_-;-h.~ps.~~l.s. eou~~ .~e used_.for these.stud~!!s• :;:-::.~·~:-~·-·:. ,' ;~·:··" , • • . . .' • •. .• ... ;_ .:,;, ". . -. • "" ~ .~··~. ~: ~41.:.~;:.:.";,~~,_,...,~#'- '~~ :_.',._~,-·~·\ "-~~~'. ~~ ~ ~. ~. -~ ~- r . : ~., . ·~ •• •• .....: ;/'. ..... • . . :"". . ~ti.-.-~11~:'..::·::'~. • ·t. ~-v~i./~:)Jhy. not consider-electromyographic recordings in cas~ the·_:C.>'.::;< ~~·· ;·_:· tor"cortex ls~·atimulat:ed.'· Also," electromyography should be o~ value in .:~-< 110 deteraiininS the. relax4tion Of lUUlJCleS desired in surgery •. .' '·;: -~ .• ;· . : . ·- ....; .... : ·.. .... · .. · .: ... ·. .... : . ··< _:-·-- .. ·. .... :.',.,· ·' ..· ·:·· .-.' -~-~-.,.~-~ ~--- -~-·;,.,~,:.: :::..-:.·~·:··-~·~· ·:··~: ~ :'~~~-.·:· . i :· .. ·-:~~X~~·: ~F~-:8~-- .v.s~·:·. -Methods for determination of the-depth of anosthesia ·are·~-;,:: · ~-- ·. _-,·:{~·presently unsatis~actory. :.Pinching the ear.. is used_ frequently with.:the monkey •....- .· -. .. : . < , : .· : .. : : ~ : ' '. ; J ; " : t . :. r . : . _~ . · .. ~ .-. : .: .·1 ,. ' . i : - _ . g ! ~ .• , .· .. :· .\ V .:.:. .. .It • . ·•_ : .: ' , -· ·. P o , s ,_.· t- ~·4. O ., : p · • ~ .. r ·~. a · .. t .. i ~. ve ·: · .; o <£; b ·. • s · er . v a -. t ion . . s-in ·~:. s ... . o . m ,.,.~ e : . ca .• .. s ·... es s . .. · h . o . uld . . b . e ex . t . . e · n ... d . e : d · ~ ~_ - '. ~ - ; . - - .. . .:~~?_~_/:~ ~~- _se~~r~t···~!~ :-:_-:~-:~~;·'>· . :~::~:::· .·~·;=\;::-_'_':-: -:i'·~_,·· :~:-. =~=~_;·.~ ·. . •. . : __ -:/: .., · .·" .. - = -· , . _;··-·, . . · n ... d . e : d · ~ ~_ - '. ~ - ; . - - .. . .:~~?_~_/:~ ~~- _se~~r~t···~!~ :-:_-:~-:~~;·'>· . :~::~:::· .·~·;=\;::-_'_':-: -:i'·~_,·· :~:-. =~=~_;·.~ ·. . •. . : __ -:/: .., · .·" .. - = -· , . _;··-·, . . . .· ·. , . ·:-;, ··::·. :'. ~~s;~~/;,:: ~-b~-·. ~>Suggested· -~"­ V .J' .: wave form combinations :seem unnecessarily. cempli-: ---:~-·.·:'.::~ . cated!i.~ Since· there· seems: tc) be· o species difference-·for animals, why plan such=:.;}/ ~ ... _.\: ~ a· compteta. series-o~ wave· form· canbina~ions for studies_ involving only clogs;._._· ...- ..~ :~ ___ - ..... -.... _.:.·l .._ :, .. ~ .~·~: _;:_~:(~~:.- '···-~;·:..:";~ ~--~>- ,, : .......... •• .._ .' ·: .... :· ::. ..., · •• •. __ :. . - ......... ·-...~ -· •• ~-~~- .· ~~--- .· ~-{:,:; -:·,~·- · · 3 ;~ ._.. coneerni'nf the- budget for this prOposal~- ·too ·many dogs (1~ 100) . and un·\\:~· · >. . _· ;_~.:-·· ·_ necessal'1 surgery_-are · p~Dnned~ · ~o continuous -recording equipment· f~r V. 'B. :.is · :.,;'_ _--__ ·. -- ... ·. :·:: ... .. .: .· ·_<;·--: -~is:~~~.!~.~l~, ;.~~i~-~-~~~~:·.tr~t7~-~~~, --~:··. :~~~-~ ·~-.:~.,.~~ --~.-~·_,_ ;~~::~-:::)·:::\:~:.~:~;.:~~b:~-~:·~ ;:~}f:::: ......- .:.~~~;~_·. . : 4 •. If 1 reealf_.corre_c_tly, the 'statement was ·made· that Dt; . .t.in 2'.year~·\~; . . ' :·~~~-.~:::-.~_:,>will obtain .a ihD. . ~gree ··in physiology. Although ·Dr. : !"is a··wll·qualified:J.={ · .· . . ·· -.-.~~-<:: D.V.M~ and ·experienced in _electro•anesthesia .with animals, will there be a neuro-·-~~· .. :, ·:-;.·,physiologist consultant· in the proposed program o~ researc;h'l Also.-· an.-.electronics · · .::1\;~>\.-.enginee-r should be available~ .. Tbe Project Proposal does not list the qualifica- i ·:l.}'}:~; _t ions ·of Dr. - . . . . . . or .any of the· te~hni~~l ass~sta~~~ a~s~!-at~.. d wi.,tb._·;. • :__ : £-.::·~~~:-. ~:, -~~~f~ · - \:~. ~~}·.--~ :·:.;-. .: :-::·:·;:~:E~=~~~2 ·--~··:::~~ ~-. ;·:·~J~~.~:-.:~ .. ·--/.= .. ;-~ --.:-- ?. ·t {- :·~:~ .:.:: :: ~:: ~~x~-:~: ~;: <~_-·}.-~.-. ~~-:<·. · \ .· :;_: ~ ·<·=?-'?r·?( · . ·. s.·.'·; I hope my eoiumenta ·aJ;e ·not. . tilterpreted as opposing the awarding of a· ~ ~ :::'~· · . : . <-)\:~-contract· to Dr.· . . . l: He:: iS highly motivated;·-; interested and experienced iii• · · ·:::: :_ .. ..::<.:'!~·:£~.~-:the field· of elact~o-anestheaia and 1 hope that_bo can modify his program eoiumenta ·aJ;e ·not. . tilterpreted as opposing the awarding of a· ~ ~ :::'~· · . : . <-)\:~-contract· to Dr.· . . . l: He:: iS highly motivated;·-; interested and experienced iii• · · ·:::: :_ .. ..::<.:'!~·:£~.~-:the field· of elact~o-anestheaia and 1 hope that_bo can modify his program to"::_~;(.;.:_.:.::;._ ........... - . . . : . --~ ":-.: .....• ! ... . . . . . . . . . - · · ,' . .,.. :. .... · .... . ·- .... -· ... • ~. 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