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Doc 0000184423

CIA

This CIA document from January 7, 1953, requests an investigation into a new compound, SPIRO-OXY-BARBITURATE, which reportedly caused uninhibited and derogatory reactions in patients during experimental use.

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--Office Me11zor art.;tt11Z • U0,TITED STATE~GOVER~~E~_I --> / .~:, A //I -:'- TO DATE: 7 January 1953 A FROM nica SP.;), I&SO SUBJECT: F.equest for Office Investir,ation Into New Compound 1. During the writer's recent wrjter met and in a le enga~ed a rankins staff member of the Department of Anesthesiology. ho is regarded as excep '·'*'""'· tionally al:le by his associates, orm 't~rit.er thrl t -in the recent !2 ~as handled, experimentally: a neH compound for the~ /:.; 2. -,stated that t was worki.nr; on C' /3 expsrin1~nt~~ds to either displace or improve on the <J.1ready Hell known barbiturates. He stated that they had sent him a nd and n:- C quested that he try this durin~ operative proced11re ..- • he gave it to a very conservative member of t B aculty during a minor throat ooeration and wo successfully for operative purposes. He stated, ho·..rever, that iuring the recovery period, this compound produced ve_,ry uninhibited re .'lctiom: on the part of the subject. He sLated that tor forty-eight ho,Jrs after the nse of the drur;. this conservative memb<?r of the faculty had talked at great len~th and in a r~_r,hly deroc;atory m.:mner. -'lbout the r~culty, about the administration he §Chool, about certain profes- sional secrets at th had cursed, had wandered ~ about the corridors and ha s to attack the nurses at the.__. : ~' '~ 3. The writer aske-if he had tried the compound on C... other patients and he stated that .he h~d done this, thinking perhaps an eccentricity ex is ted in the .?.hove· case, but the comnound reacted t.he C.. se1me on the other two cases and,:· thereafte ad ab<mdoned all use of this chemical. ... Lt. Thereafter, the wriLer, without rttteMptinp; to crea_te reqnes t.ed th1.: name of the chemical fro'TIIIIIIM • •••• sLated that it ;,.;,1.s known a~ SPI~O-OX_Y-!3AIU31TUH.ATE. s ccH~o, the writer had an in.formnl ccnf'rorenc"! Hith of the t1edi caL ~itaff concP-rni.ng • • • ctncl, -'lt s C<1nferenc'2, thP 'tJri Lor tol.d tk: -'1hovr~ story l:o . · 1 <1d rraveA him the n;:]me of .t~n qucs Lion mvJ m:1clc ;:> n inf'rn·mn.l rcqw~s L ,A at that time th8t~ave this compound check~d to determine whether or not it had AF.TICHOKF. value. :· -"-:~;--~::~~~ . ~ ~~ . : ~.~~ J , ..- · ~~-· ~ .;:~"r'~ - ~~~:. ?.:-~·:, .. -:;.~---.-~~::: ~- : . -~J..-~. ... The image is predominantly black with a stylized title "THE BLACK VAULT" in white, neon-like lettering. To the left, a blue-tinted, detailed illustration of a round vault door is visible, featuring various dials, levers, and a central locking mechanism. The text below the title explains that the document was obtained from "The Black Vault," an online database of declassified government documents, specifically referencing the MKULTRA/Mind Control Collection. The text also provides a URL for the collection: http://mkultra.theblackvault.com. There are no photographs, handwritten annotations, official stamps, forms, diagrams, tables, redactions, or visual evidence of experimental procedures present on this page. Lion mvJ m:1clc ;:> n inf'rn·mn.l rcqw~s L ,A at that time th8t~ave this compound check~d to determine whether or not it had AF.TICHOKF. value. :· -"-:~;--~::~~~ . ~ ~~ . : ~.~~ J , ..- · ~~-· ~ .;:~"r'~ - ~~~:. ?.:-~·:, .. -:;.~---.-~~::: ~- : . -~J..-~. ... ~· ·~3 )~ --~:-.. - ;. > ~· .... _.-.::\.: ~ ......; ~ '.. . ;.; ,i~. . ,~ (~·<··-.-- ... ~:.._' ·. ·~-·~ p .... :· .,, ... _.. J ::.: .. ,,.. . 6. It is sur;c.:e:::::t.ed that you turn over -:1 copy of this memorandum with your approval to the CbiC>f of the ;-iedic:<l ~:t:1ff merely for th~_ L1 411p!u$r n?se of confirmins in wri tine; the infonnal request mc:tde of lfl jos- mentioned above. ·•·'-'. A .. - - . • ; -2- r·· - -------------·----- -:· ~ J "':_ ··~. •c:~. ,·1 '. ' ,.r ~ t - ' E \ M ~R~ .. : :·: ·· : .. ' ; ! - iy f l ; ' . . . , r,','• ''1 i i <I; , , , ,, .: ~· j • '. ~:Herewith· is:·:' self-explanatory memo in [l case of the new compo.~ .t ·I h,_,ve ~;informally requested._ to re.:. :search out. ·.:I think, .how~_vehra t you could send a copy over to~, OTS for his, informati . .p n · ., ... ::- ·- · ., ~ , I will take. !'.•· ~ra~ly_when I' I BUILDING 13 ••t ' . • -1 I ROOM NO. 36 8 FORM NO. SEP 1946 • The document is a scanned, typewritten memorandum with significant redactions marked in black ink. Handwritten annotations, including letters (A, B, C) and possibly initials, are present in the margins, likely for categorization or review. An official stamp is visible at the top right. The content appears to be formal correspondence, with fields for "TO," "FROM," "SUBJECT," and "DATE," all filled in with typewritten and handwritten entries. The extensive redactions obscure key information within the text, hinting at sensitive or classified content. The page contains typewritten text and several large, black redactions. A numeral "6." precedes a sentence that appears to be a directive. The letter "A" is written in the margin next to parts of the text, and another "A" with an asterisk and three dots appears further down the page, also next to a redaction. A page number "-2-" is visible at the bottom. The overall impression is that of a heavily censored official document, likely pertaining to administrative procedures or instructions, with significant portions of information obscured. The document is a "TRANSMITTAL SLIP" form, dated January 12, 1953. The form contains pre-printed fields for "TO", "BUILDING", "ROOM NO.", "REMARKS", "FROM", and "EXTENSION", with some of these fields containing handwritten entries. The "REMARKS" section includes a typed message and additional handwritten notes, including what appears to be a name or code. There are also handwritten annotations and marks, including the letters "A" and "B" in the margins. The document is marked with "GPO" which likely refers to the Government Printing Office. Portions of the document are obscured by heavy black redactions, particularly in the "TO" and "REMARKS" fields, as well as below the "BUILDING" and "ROOM NO." fields in the "FROM" section.

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