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This CIA memorandum from December 18, 1951, discusses the potential use of carbon dioxide therapy, as described in a book by L. J. Meduna, for "Artichoke" purposes, noting that the treatment can induce unconsciousness and a willingness to talk.

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- t ,._. ,. A$, • 6'TA:lOARD FORM NO. 64 63/1 Office MemorandttJJZ · uNr~En \TATEs GovERNMENT TO : file DATE: 18 Decen~er 1951 FRQM SUBJECT: Carbon Dioxide Therapy, Possible "A.rtichoke" Use l. Reference is made to a book entitled CAKEON DIOXIDE THERAPY by L. J. Heduna, 11. D., Professor of fsychiatry, University of Illinois College of Medicine, Chic~go, Illinois. •2. TI1is book set.s forth the treatment of certain types of nervous disorders or psychopathic conditions 1:>y the use of carbon dioxide (C02) mixed with oxygen. Dr. Meduna has set forth in this_book his techniques in the administration of c:J.rbon dioxide trea.tment on: certain types of mental patients and, in general, it may be stated that he uses, for medi cal purposes, JO;\~ C02 mixed wi t.h 70% oxygen. Dr. 1'1eduna uses this mixture by straight co~mercial purchase of the mixed sas in Chicago which he buys for approximately ~r9. 75 a tank full. This gas cor1es in tanks which con tain 1400 gallons of gas under about 1800 pounds pressure and is delivered to the patients through two manometers into a standard breathing bag, gas inhaling device. J. Accordinr, to Dr. r-ledun2., the inhAlation of this mixture rapidly ir:duces unconsciousness in a patient. This is held for ~ m-'lt.ter of a few seconds when the mask is removed and the patient then regains full consciousness thro,Jgh a so CCl.lled ''transitional" period. Aoparently dur:ing this trMsitional period, Dr.,"rleduna qu~stions the patient and also at this time the patients talk ~ver or tell about their experiences in the sense of a psychiatric treatment. : ~. This book indicates that by the use of a C02 dosage, mAny in- dividuals have talked at great lengths of their past, revealed intimate secrets, abreacted, etc., etc. and because of this, Dr. M8dunn has ap parently achieved some excellent results in treating certain mental condi-t;.ions. 5. Although C02 treatments apparently produce intense dreams, hal lucinatioHs to a certain extent and a desire and willinfness to talk, the writer is doubtful if thifl C02 treatment could he appli8d to "Artichoke'' unlPss it wns ,1pplied ;liter the individuill had r·een rr:ndered unconscious, since the treatrr.ent involves the use of a gas m:=Jsk ,1nd cumbersome equip ment. However, it might be ·0f int8rest to ex~rnine this t~chniqu~ with the vi<?w toHard filling an air-proof room with ,q similar ~A.s mixture (Jo;s C02--70% oxn:en). - ..... .... . ,.. This image is a screenshot from a website called "The Black Vault," which hosts declassified government documents. The visual elements include a stylized graphic of a bank vault door on the left side of the image with blue light emanating from it. On the right side, there is text describing the source of the document and its availability online. The text is a heading "THE BLACK VAULT" in stylized white font, followed by a paragraph explaining that the document was obtained from The Black Vault, an online database of declassified government documents, specifically mentioning the MKULTRA/Mind Control Collection and providing a URL for download. There are no photographs, handwritten annotations, official stamps, forms, diagrams, tables, redactions, or visual evidence of experimental procedures. individuill had r·een rr:ndered unconscious, since the treatrr.ent involves the use of a gas m:=Jsk ,1nd cumbersome equip ment. However, it might be ·0f int8rest to ex~rnine this t~chniqu~ with the vi<?w toHard filling an air-proof room with ,q similar ~A.s mixture (Jo;s C02--70% oxn:en). - ..... .... . ,.. t"9, .. 1' 6. The book does not indic.?.te any extensive use of hy-pnosis or l auto-suggestion in connection with the C02 treatments or the use of C02 as a means of gainine hypnotic control. 7. In connection with the above, it might ~e possitle to have C02 experiments conducted along with experiments on low oxygen content or high and lmr pressures in airtight rooms. 8. It is suggP.sted that ~.i_ :nformation t:e made available A to the medical staff (perl-)aps .._,-or to , or a future discussion with .'medical or psychiatric consultants· o{--' this Agency. 9. The cook, CAP.PON DIOXIDE THERAPY, appar~ntl)C c<tme fror:1 the Army ~1edical Library at Washinr,;ton, D. C., and the library number is QV Jlh ~lh9 JC 19 50. - ( .. _ ... ·. ·- ... ' . _.. . - • ~ • . ' -r-:--~· ~ . -- . . . ~ . . s ~ ";- ·- ' . ' - -·. "<· ·:.-........· ' ... ._ .. -~ ' -- The document is a declassified U.S. Government office memorandum titled "Office Memorandum," dated December 18, 1951. Handwritten annotations, specifically "A/B, 1, 63/1," are present in the upper right corner. There are several large, black redactions obscuring text in the top header and a smaller redaction on the left side. The top left corner of the page displays "STANDARD FORM NO. 64." The rest of the page consists of typed text detailing information about Carbon Dioxide Therapy. This document appears to be a typed report with some handwritten annotations. There's a large, handwritten letter "A" in the middle left of the page and another smaller "A" near the center right. Several sections of text are obscured by black redaction marks, particularly in points 8 and 9, and also in a scribbled line across the top right. There are also several small dots and dashes, possibly indicating formatting or corrections. No photographs, stamps, forms, diagrams, or tables are visible.

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