Doc 0000017394
CIA
This document is a memorandum from the CIA's MKUltra program detailing the approval of funds for Subproject 135, which aimed to provide a reservoir of volunteers for scientific investigation.
This is one record. The archive holds the rest — ask it anything across the MKUltra files and every answer is cited to the page.
Ask the archive about this →This page displays a prominent graphic of a bank vault door, suggesting themes of secrecy and security. To the right of the vault, white text overlays a dark background, announcing "THE BLACK VAULT" in stylized lettering and providing information about declassified government documents, specifically mentioning the MKULTRA/Mind Control Collection and the Central Intelligence Agency (CIA). A yellow-text hyperlink to "http://mkultra.theblackvault.com" is also visible, indicating a digital source for the information. There are no photographs, handwritten annotations, official stamps, forms, diagrams, tables, or redactions depicted on this page.
I - .. I . ProJect ata.lLfRAI- SU'bp~eat 135 -- ~'" ~ I I Date Wt1aW4a 15-=:~w&Nr-1~ __ 1962 .\. D&te &xpil"el. 1 Octobel' ) klt,810.()0 ---------_ --- ~t-~l_ __ ·~---·- .t Purpoael_ ..ro p~e~tot~~veati~t1cna_1~V()l._~-c~e&1 teatioa ot-~===-==-~=-= 1 volunteer• .in~ ot-TSD iDteteat;-'the proJect vill provi~ ~-- _ I taoU1t1 ~ a_teu_ot ~~.J.~·aupii"Viaon·u-wu ,a-alM~=-~~lJ-~-c~~-~-~~~~-- I reaervoir of volwteerat'' -· - -~- --- - / ' "' .......... I . !! I ' i I I I I I I . . ' . ' ~' ·. . -. ~ . ... ~-~ ~-~~· ----~-7-~--~-----,--~'·-"'---:--~~-- ~-----~-- ~-~~- .. .... ,· ( ----No. ____. ..,~.A~'.I!!:...PL~--- J/JS- Rfl -J?t~,;;. Date Remarks_imd_R~f_e~n_~ _:_-==~-~ ·- O I b n l c ig u a r t t i e o d n s - O L b iq li u g i a d t a io te n d s . - -- U - n B li a q l u a. i ' d lc a e t ed .. -- :ss-- . .... I :3 .... U June l96L __ M£MOrtANDUM FOll: -_ __ COMPTROLLER . ATTENTION • -----,--- ·--- SUBJECT • Under'':t'ho authority granted tn t~_melnp_r_•n~~m date<llG_June ____ 1961 Crom thi; DCI to the DO/A~ and the e)ctenaloiLOl tl'lls-_:autborUy In subsequent memoranda, Subp_rojaeri3S M5 b~fen approved and $25, 868. 00 _ / TSD)Uesearch nraifel1 __~ ~-\ PPRdVEl> ,fOU X OULIQ;\TI()l\ OF_FU~DS: -- .. 7" H~searcb L)lrector - tai~'i Date~ Distribution: Orig & 2 .. Addresse c: l - 1SD/OC tJ.--L IF TSD ASS 2 • 'fSD/HB __ _ - z ----------~, i I I I ! l . I I ~ FOilf --cuui~~-VIYISIOI-- , ..: · ' l YIA · l !80/~t Qtts.~~ "~-"•~,-'-•'·,;o',"' ••_<-•: . .,_,;• ~·f·~{• •'~· •r>" ,J' •'<.,.,., ·~·-:._~,r.CJ ~,~·;•.-.• ~· •• '-. I ··). ! ' ~ SUNICI~-~-HMaM~sw.PN:.Oc"\ _13,,- IQyotc. 11 l - · I Wb.mtnt:_2.125-~3202· l i ! lI . lL_Ifivolcelo. 1 COVOJ'Ing tM-DlX>V.--.,.'bproJeo\ it_ e.\~·----- Jl ~t ~ll4 be .u-u toUOVII I ~-- p: S!.=:~~~~~~-•=j,J'1flal-i!!~_lc-.~- Bowver,- atnee 1 t .la ttiUelpaW<t --- tb&t ad41t1ooal.::_t\irtla:_vt)l--:_bi_~ilp~~t01-=:thta_:proJtCot., ~ tU.et-_"; ahoal4l:!Q\ _be_clOR\1. · .- ~ '' M:rbl ____ .......... '"""'>~ /.r~: '· ,~'. IN'LOICE- - For · ~rvlcea tit .... - .. -Q- ---e. -· ---· CERTIFICATIONS----- (l) It 1e her..tliyctert.i·{t_e_g_ ths.~-~~_!_a Ill_v~1ee_1..._;_6P:P}Y\na to 8\lb•proJect Moo...J.lli of J.otJJL'l'RAI-tblit-~rf_clr:!Zl@~e-ia 8!\.t_iafactory,that. services are 'N1ng accOtnplfshed· in aecol"<lan~~-vJ._t.ll. __ tll\!!-.\lal agrceillfints,=- the;.t~a_:_~e~U~sl__~gcf!i¥-ot the payments and::::.me.eipt-8-Js on fUeccin-TSD/RB;=tna.t~lhis_-b_ill.~ts~.Just and-..;c==~---=-=- --~- correct and
The document is a typed report with handwritten annotations. There's a handwritten "135-1" in the upper right corner and a faint handwritten symbol resembling "-c" to the right of the text. The report details Project MKULTRA, Subproject 135, including its initiation date (September 15, 1961), expiration date (October 1, 1962), and funding for the current year ($24,870.00). The purpose and status of the project are also listed. There are several dark, rectangular redactions scattered across the document at various locations, obscuring content. No photographs, diagrams, or visual evidence of experimental procedures are present.
.......... '"""'>~ /.r~: '· ,~'. IN'LOICE- - For · ~rvlcea tit .... - .. -Q- ---e. -· ---· CERTIFICATIONS----- (l) It 1e her..tliyctert.i·{t_e_g_ ths.~-~~_!_a Ill_v~1ee_1..._;_6P:P}Y\na to 8\lb•proJect Moo...J.lli of J.otJJL'l'RAI-tblit-~rf_clr:!Zl@~e-ia 8!\.t_iafactory,that. services are 'N1ng accOtnplfshed· in aecol"<lan~~-vJ._t.ll. __ tll\!!-.\lal agrceillfints,=- the;.t~a_:_~e~U~sl__~gcf!i¥-ot the payments and::::.me.eipt-8-Js on fUeccin-TSD/RB;=tna.t~lhis_-b_ill.~ts~.Just and-..;c==~---=-=- --~- correct and that ~J'!ll~Jlt tr.irQ9t has-not·yett5een=ttAd.e. ____ _ ---------------- -___ , -_:_i-""--=-=--=----==-o=-- -.=_,.--_ =---=-oo-=::_ Chief, TSD/R~_search--ara.ncl'r (2) It is r:<::r~by cert.ified=tll..at-th1s-tnvotcc-applies_to SubPi'oject-l35 _ of K.WLTP.A v:1ich_vatLdulY approv-ed,-and-that the pr9Jeot ia::_~e_ing _cari'\id o.1.1t __ t;o- in accoN.ance Yith .the_ _ ft!41JnQrandu:!-:::Q.f _1_3 April-1953-froo-the OOl t/neJ5I5/A 1 ani 'the extenoion-ot~ this authority in ~u'l,)~e~quenCii.)!moranda. - - - Roacarch Director ··- .......c (When Ff'i+ed ln) CONFIDENTIAl FUNDS POSTING VOUCHER '-.S) VOUCHER NO. 7• 12 DATE 2• 6 VOUCHER NO, 7• 12 1\ r6800- u. -.,--,-..-fz ~ ~ ---------~-:-f'IF;.,:.r...:._,z~""· T . I : A , N 3.. O ,3; 3 . . . 3 : :.~-l ST 3 C A 4 O T · D I 3 O E t N E 4 X 0 P . E .u N D • U F 3 PAY R O E l F l , L IG NO , , 1 53'' 54,57 I ....... A o C T 5 C . T 8 , O R ~ N O C . O ST - D D A U T f E . .. "" A 7 M 1 O · U e N o T -... "' ~. • o . , . ' M ' O ' , ' ' P " "O " P , • " N . O . . CODE N P LI E O R .,..• e.,.•• w• c• F• . .. CA G ! E .E N D E G R E A R L 1 N:~~- 1~:~~~~!1 r 1 ·1 • · • •• . •• . • . , . 3 . l f 't ' lt . '> : l T b;00' " , ' ' F · .'cT N ' O "k . . : 'V S O COO~ -~ £ - M ~' r . . ' . N ~0 O . . ' . YR ACCT. NO. •,; ;;;." ~~: Ct. ASS COEDIT I S - rrI I . - - .f. ! - I _ . .v ; I • I . - . . • I I- , - ~ •- .
The image shows a page of a ledger or accounting form with a grid layout. The form includes fields for "Date," "Remarks and References," "Obligations Incurred," "Obligations Liquidated," and "Unliquidated Balance." Handwritten entries include dates such as "24 JUL 1961" and "2 AUG 1961," with associated entries in the "Remarks and References" column and the numeric columns. There are also handwritten notations at the top of the page, including "135-2" and "139." Some portions of the page appear to be obscured by redactions, particularly in the upper right and lower portions of the image, indicated by black ink. The "Cost Account" field is filled in with "2125-1390-3902."
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The document is a memorandum dated June 16, 1961, concerning "MKULTRA, Subproject 135." It details the approval and obligation of $25,868.00 for subproject expenses, to be charged to Allotment 2125-1390-3902. There are handwritten annotations, including an "A" next to "Original signed by" and what appears to be a signature and possibly dates in the "Research Director" and "AUTHORIZING OFFICER" sections. Notably, there are significant black redactions covering portions of the document, particularly in the upper left and upper right corners, as well as a larger redacted area near the "Chief, TSD/Research Branch" line. The document also includes a distribution list with checkboxes.
• I , I I , '• I I I I ::, '• . 1 • : I i ' ' \ . I . .I . . • I , I . , t • , : ' : • t r I l : I t . ' 1 : t . . , . • 1 • . . . . . . . . •I . , ' ' • I . I . . . . ' . . . . . . . . : o I I I " ,, , , . . ' i ~. 1 ! '.. 1 . : ' ' . . . . • tl •• , .• I I f I I t I I I 'I I ' 1• ••••• EXPLANATION Of ENTRY TO~AL .Y.~J . I· .___. . )i AI A'f-~ .L.-1111':_ _ . I I '!I .! PREPARE ,, D BY DATE REVIEW£0 BY ICERTJFIIO:OFO~PAYMENT OR CREDIT ~ ~/"'" ! Ii I : ,1.' ' i D i ATE I'IS l I • G il N ii , i r i I 11 ;URE I . · C j ) l F ! C ~ !1 . !: !R ·: T , i . f ', ~l ;: tNG OFI : ';ICE I! R F 1 O 0 R ·5 M 9 606 USE P .. !tVIOU'I 'trD ITIONS, i (10•UI i I I .I " (~n) !:'- SUOIIIITTEO BY J«Ul.Tfu\ SUb l.35 ACCOUMTIMG BY INDIV!DUAL ' FOR ADVANCE ~ \1 NOTE: I I 139 OA'I'E I rORIII 282 '''('II,, ,, ! . 8-61 US! P •• YIOUI EDITIONS. , fc::.OL~.PI.J.f( Cc;P '/ ' ' 1,, I -I I --· u .'.L..--r.-- ~ ~- - -- - ---- I ! _____ ! ~M-• ---s.:..~_- - I ( fJJBJJCf I Jt.a.&'m.\~,_191 -~1__1!~u4 ·13, --::=:-=-_- =~ ' ' . - f ·'f:. ' ~-~~!'!~~~-~L~~.!autit-or ~NOJfJmA. tv-.~-perlod -- I I ..,..,~ 1 tt.CCOWltms. havo_l>OeG ro<:ei'\"04 • ta· ~of ~93,611· - . - If) balaMe to be ~W4 ~- ·i L,.. ···-~--&t,-t.lji_ij'Q4 ot~&U4J,t I I ; ~ 70-1JiQiji~~~c1NC\ c~ Of ~.514.3\. ~-~ ,8'n!l6 f 'tre.r~-fml Bub~\ ~~-fOro-& tOtal-Of-.3(),'¥»•50• ~i"=~-~'----c~--=--= -_- I fj4. ~-~~-ot"C~$1ll324"·87i-'Wt-tri0iti'~~~~l.65·11··to·Sub~=.-~----·cc_c----.-- • ~ J~ 9J. aftd_$27,872•16 \OSUbpro.Je¢\ 70 let.Yi1l6. mt-cot\_ot $)91~00 • 1 I~ ,.. 4Mt4«\ ~w_cU'lfl'\-_'\.liij=~_,~=-~ :l.35_1o -~,s.."ti. 91, oo:Jto .... ~ ~ toclu4«4-s.at»·~_ft(.a WbprOJeet.-91.-=-=--~---- ~ u:_ 1) &U tou at tM aubjt_~q mil-~..-
This document is a typewritten memorandum from July 1961, likely concerning financial transactions related to the MKULTRA project. The top right corner has handwritten numbers "135-4." Dark black redactions obscure specific names, amounts, and other details throughout the document, most notably covering large portions of the payment details and recipient information. There are also handwritten annotations, including an "A" near the bottom center and multiple entries of dates and amounts that appear to be related to payment authorizations, with some entries also being partially redacted. The document appears to be a standard administrative form with fields for "Attachments," "Distribution," and "Invoice & Certifications."
The document appears to be an invoice with certifications, likely related to the MKUltra program. Visually, there is handwritten annotation "135-5" at the top right and a handwritten "B" on the right side of a large, dark, redacted area. The document contains a section titled "CERTIFICATIONS" with two numbered paragraphs. At the bottom of the page, there is a line for "Date:" and a signature line for "Research Director," implying official processing and approval. The presence of the large redacted area suggests sensitive information that has been removed from the visible record.
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This document is a declassified Confidential Funds Posting Voucher, form number 10-59 606. It contains a table with various fields for accounting and budget information, with some entries handwritten. Notable handwritten entries include "Support 135 JAN 1", "MX ULTRA", "8821", "134", "601.0 25-1310-3912 752-255", "$70.00", and "998.00" in the "CREDIT" column. There is also handwritten text in the "EXPLANATION OF ENTRY" section that reads "See attached" and a date in the lower left corner, "8/7/61". The document also has "135-6" written vertically on the left margin.
This document is a financial accounting form, likely an expense report or voucher, pertaining to the MKULTRA program, identified by the name "MKULTRA Sub 135." The form details a period of accounting from December 1, 1961, to July 31, 1962, with a total amount accounted for of $24,000.00, referenced as an advance. There are several handwritten entries and signatures, including an "MKULTRA Advance" description and a signature with initials "A." Parts of the document, particularly in the "Signature of Approving Officer" section and along the right margin of the main body of the form, are redacted or obscured, as is common with declassified documents. The form is typical of governmental or organizational financial paperwork from the era, featuring structured fields for dates, descriptions, voucher numbers, and amounts.
iii funding or - · variation in fisc;aly~r_js~~~p:~exy.~'_d~J!lis-lij:ili_e-f~~-~~-' / TSD7Research:Sra~ch ___ 1\ CONCUR: ( ; Distribution: ________ ·~~..~,~,. ...... SerVice~(:::DiVis_t<>n ~-------Origin~l only-- Date: ");-4~·;. -----------------~'~~illllllli /3 s-~tJ P~~--f'omM=tti4t_::::_i_ : D_IR_~~~--~--_Cb1,t 2 -t 4 - _IJ.'SO/Roa~ Bran~~--- - - ottteer, ao later than lUlJ-1961· .. · 3.-ttd,-t.aa ttMllilvolo4fi- B<Mwrl ain~ 1t la_lllUc1~t44 - · t.ba\ a&Ut!®al N?4e-:::Y1U_\ii Obll&&W<l-tortbla proJe~t, t.M tUet~ ah<;uld oot _l>l_cloMd. At.tacbeat.aa---- lnvolee • CcrUfie&t1ooa - lilatl"1b\lt;1(1QJ - -c :c::.::::~ :::: ~;---=----__ Ol'ie • a • - /l.Mneeee ..... l ... '!SD/FI.BS _________ t..2- Tb"'D/RB ____________________ _ ...,A- ~ ' ,"'· .. »;' ~. "' • "if - • . 1 : ~ ' - k ·-~ -• - : ..· ~ .. INVOICE -- -- For Services -.' ---- - - - - . -. - - -~-~-~- ___ C&~7FICATIONS (l) It is here'by_~arct,ititt~~is 1s=;_InvQ1§e-=.c.:.app}~tc.L~ru.b~pr2J~c!_ _______ _ Noo...,__l.J5.~-..o f MKULTRA, -tha!._~rfoi'!IlMce h sat~a_factor;y,uthat. services are 'being __ _ _ accornp.lished in accordan~e::_v1th_mut!l8l_jigxoeements, tl:Jat-::a_detailed:_agenda=-ot--~-=----=-. the pe.yments and receip!-!_is~on. fi_le in TSD/RB, that ·this 'bill:::ts=:-Just ·~--=--=~-~--~- correct end that payment thereof has not-yet been 004e.__ _____ Date: ~-----,------~·-------~~· ----- (2) It is hereby C·~rt1fie<i t'l:lat this invoice S.lipliee to~ SubProject _clJS of MKU!Il'M vhich-va-1.3-duly __ jl.ppi'oved,~®d ~t,p~J.~-~!l~_P!'O.Ject ia_:_beln_(f_earr ero n ut _ - __ : :_ : _ . --- in accoNAIH!e vith the -ll!e.noranduf!l-ot'" l3-c:.A.prill953~trOttt the_OOl to-: the DD/A; - ---- too e.nd e:;<tens1on.:..o!:::_th1Le.llt.'l~rlly in subsequent me~noranda. _ __ __ ___ __ _ _ • " ' ""'.. -,._·: ""f. • : ' < t' ' ! . i1 i . I i ATTENTION ' SUBJ&CT · ; · ······_ M~UL'l'Rt\1 S\:.bprojcct US ________ ._ Uacler the authorlty_-gi'&.nted Ia. the m•moralldum_dated_lf_,J._.aue ·'tell from the~D~IJO']IW_D.IiLA. Andlb4:_el.tenalort ot llde~a-uUtorltt JrL __ subsequent mcmor-anda-;-:~'ubpro}~l lJS Mi_~~l!_aJ>proved and i2$, 868. GO of the over-alCMKU_L]'.RA-::-projict-ruada has been obligated to cover. the ··ubprojeet ••~a$es:;-ThTioblljiltouor fundi--inoQld btt cbarccd t.e>. A"!totmcnt 2n~-1~90·39t]l~ ~ = l •' I APPROVED .FOU _ OBl.IOATION OF FU~DS: __________- -==' T>t~.te:. - Distrlbutlot~:-- Orlg & l ·o-.'\ddrosse e-__ 1 • TSI:i/OC . _____ _ 1 .. ,TSD/FASS ~~-TSD/HB ). DRAFT----- L6 June 1961 __ SUBJECT 1. The purpo_~~~QLll\iSJSul>project is top}"OVide fu*ds_to_:~arry out - a research of hurnan subjects. prograll'l~iny_olvj~tilizatlon vol~nteer to_ 2. This progra_!!!_j~_de_~igl'!~d ~xJ)loit clinical an~ laboratory ~=~ facilities and ptovidirig ans\fers to spEtcifici ·_- professional-_kn9wle_gge~h'( questions of direct_inurr:.esLto th:e___Ag~I\~Y· Tne nature of the investi gations to be carried out encomp~!lsesp]!~mac()l_ogicCll and clinical- ~-=----=-- testing in human_volunteers_oLch~_mlc_a}s;-biochemicals;_and.hiolog~AUY_ active materials=-under:::::controlled-eonditions. Forexampte;
The page is a typed memorandum with handwritten annotations. A number "135-8" is written in the top right corner. There are several large, dark redactions covering text throughout the document, particularly in the middle section. A stamp is visible on the right side, partially obscured, that appears to be a "3A" designation. The bottom of the page contains a typed signature line with an additional handwritten notation above it for "Chief Scientist, TED".
out - a research of hurnan subjects. prograll'l~iny_olvj~tilizatlon vol~nteer to_ 2. This progra_!!!_j~_de_~igl'!~d ~xJ)loit clinical an~ laboratory ~=~ facilities and ptovidirig ans\fers to spEtcifici ·_- professional-_kn9wle_gge~h'( questions of direct_inurr:.esLto th:e___Ag~I\~Y· Tne nature of the investi gations to be carried out encomp~!lsesp]!~mac()l_ogicCll and clinical- ~-=----=-- testing in human_volunteers_oLch~_mlc_a}s;-biochemicals;_and.hiolog~AUY_ active materials=-under:::::controlled-eonditions. Forexampte; human patch testing or human_bl<fod.gr_()!ll> d~f~rmJ!lations _wiU bem ounted Ufion ....• setting up a experiment. suitably~_<tf~Jgi!_eq 3. The general super----- investigationsw!JJb~~~!'r!~~-~ut u!lde~the C. vision This individual ~ilLserve as project- leader and cootdlnafeallpti:ases and of"ther~sei\:r~h p_l"_()g~am-,-select provide cHnicians::.to_conduct the •n-planning _the -- experim«tl!~· ~§~l-~t experimental design-and protocol, and supervise the preparation of _data _ and reports. Tlie_attached pr_op_osaLinliicatlfS the_l\at\Jre-and-extentof n --- - some of the investigations that will be-carried out. . . \ ' . ect u,sing wilroe-tr~nsfe!'red , __ -· . ~ i .,. ·~. i e cost of this''jfrogram for' aperio<n>f ·one y~ar_beginning 1 July 1961 will not exceed_$21, 87().Q_O. 1'~tthis_s_wn must be added::-$998. 00 representing a service-ctiarge to 4~ . . .· . . . ho -will act as a Cl.lt-out,-• making t\h e:! totata-mount $25~-868; oo. ----- - • • . . . \ "'· . 'l . . .. .---...... •o-.-•:. -,.~·;<· ... -..... -·.·<:.'--<·_-,"- _.~ ..·. ---· ····-·--·-~~:<··"'" ,-.~· ...... -~-.;··-.-~-~·~~..,. .· .; ... ~. •' ._, .' .. , .._.~ . ~~~--~··· . -· ~ ~ (3_...,. _· __ 1~ r·equir:eo~hej>l'lncE 6. =-'----------- pal inve~Ugato'~~who.adrnb1i~~th~~g~·to'submiCto'tnem_-'tfsJ1fum_ary . . ... B a~couriting upon ·a~_annuaLb_asis.:.:_O_r_:_alLmon_le~s_::_r_e_teived from~_the Also they will require-that any unexpended funds be returned.as_'soon_as. ___ year.- --- possible upon t~e elostLoLthe~-grant 7. -The requirement for a six months' informal~accounting on _the part__ of the principal investigator is-waived •. 8. ·It is not anti~ipatedlhat any permanent equipm.ent_wilLb-eurequlred for this program.-~---------------------- _______________ , 9. It has been·agte,d that--~§::culllentatiori and accounting for travel expenses whi~h are reimb-ursable shall conf6-rmloaceepted practices. 10. It is agreed that technicaLr_ep_Qr_ts_relli~Ung _toe progress of the research prograrn-wilLbe :accepted=aLi'nJ.ltuall)'a(fcepted intervals •.. e _:- s signed a memorandum of agree~ent and holdsa· --~---- ... . . TOP SECRET Agency· Secuti_ty~.t\greement: Ttie projecLwill be __u nclass~ ified after it reaches. ().r-1(, .. ~ . . . . . . · • · . . • ' . · ~'1' . . ' . · . . . • .. ~ . '· ,., . _ • ' ' Y · . . , ' . . , ..... . . _- . . ' . - -..
The document appears to be a financial report detailing the "Pharmacological Screening and Testing (Proj. 500w)" for the period of December 1, 1961, to July 31, 1962. It contains two tables: one that outlines grants and associated figures, and another that breaks down accounted-for expenses by categories such as salaries, payroll taxes, and travel. There are handwritten annotations in the margins, including a circled "ACCTE IN SUB 91" and a numerical notation "24,000.00-135". The document also includes several areas of obscured content, particularly a large black smudge in the lower portion of the page and a smaller obscured area on the right side of the "Grants" table. Additionally, there is a stylized "B" graphic in the upper left corner.
. . · • · . . • ' . · ~'1' . . ' . · . . . • .. ~ . '· ,., . _ • ' ' Y · . . , ' . . , ..... . . _- . . ' . - -.. _.A APPROVED FOR OBI..;IGATION ____ ·.;, OF FUNDS: (_'. Date: Attachment: Proposal & Budg~_t_ __ Distribution: Original only -·· OBJECTIVE : · To establish. a professional organiiatlon-.for thEfpfiin¥1 ___ purpg§e of servic!ng and conducting_fomplete_ clini_c~ __ evaluations and testiri.gs upon: demand. Inaddition to prescribed actly!ties,_to maintain itself on .. ·a· stand b}' basis and to be able to· mou:nt clinicaLprojects on-an-ad lioc basis:-- - - ----------- ~-·.-. __________ PROCEDURE :--see attached-sample pr6tocol'f6i"-pa1ch testing. CLINICAL FACI'LmEs--:::--______:__:::_:__-_:_::_:__--___ -_. LABORATORY PACILITIES : __- -_::-_: 1. 2 3 4 ,· c BUOOET: ( 12 months~peri6d) 10, ooo-:-oo - Principa.! ·i ri._'Y~§tig=at=o=:r ______ ProfessionaLstaff~- _______ 6, 200~00- secretarial 1,800.00 1; BxP:~ii<Ig.},}_~~-;cp~m!c;~j~-s\r[5Q;;;;;;l~ie~s- 6oo~-o-.o_----------=- _-_- 2,soo.oo Clltilcal_s_Ubjects, fee13 2, oo·-_-_.. Tiavel;maintenanc=e---~--- 300~ ,'_ Jnsurance, malpta~tice & lial5ilicy-- 470'.00~ '-~=~~~:~~- -~.;...::....;;.,;;.._ ______- .-ccc·c~~--CC 24, s1o-:-oo _ Total~---' . ,.. no overheador_fe.ec___ _______ .~ ) .- ,--'\ 1 -;.s---1£ ) PROTOCOL_ ____________ _ OBJECTIVE: Todet:ermine whether-an unknown comppUI1<!; _-_eith~r_che~J!ical_ or biological,-is -capable-of eliciting a reaction-when applied topicallt=: =_:_-:_ __ to the skin, either locally 9.1' systemically, or both. BACKGROUND : ____- :-If the skincis able to~deal With the irritant.compound, the reaction is pll.yslological or normal. However,-lf the action of the itritantis ex-~- _______ _ cessive, the-reactioc HnrathOiogteal oraooortnat-and irrltatiori- reswts-:-__:::_:___:_:_::__-:_: Irritation is an extreme reaction of tissu·es-c:to an~insult or injury and i.S. ~--- best_characterized as incipient inflammation.-< The Inflammatory process-.---::-:-::-:-_-::_:: from_a to edema formation and - ---- may=-v~ry bit~IypercepUblehyperemia) vestculation and finallyJ 9:a-=supp\J!"~~ive proc~ss. A primary itr_it~t may ]:)e_-definedas_a substance pi"odticiiig aiJ." inj\I_cy_on {ilst-c()il_taci~~cc_Tiie=I~il!t@LiilJury _y,rUI dep~11d o.t1 th6_11ature __ of the irritant, concentration oflhe irritant, and the totaLelapsed time of exp
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