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This 1952 CIA document discusses methods for neutralizing the effects of Sodium Pentothal, noting limitations of central nervous system stimulants for clandestine use and the psychiatric applications of Sodium Pentothal and Sodium Amytal as truth serums.

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The page features a graphic representation of a vault door on the left side, rendered in shades of gray and blue, symbolizing a secure repository of information. To the right of the vault, large, stylized white text reads "THE BLACK VAULT". Below this title, a block of white text explains that the document was obtained from The Black Vault, an online database of declassified government documents, specifically mentioning the MKULTRA/Mind Control Collection and providing a URL for access. There are no photographs of people, locations, equipment, or subjects present. Additionally, there are no handwritten annotations, signatures, official stamps, forms, diagrams, tables, or redactions visible on the page. \ L /1(~ I) ~~ ~r. Office Me1nora1z • UNITED STATES GOVERNMENT ~ G- .- To- Chierlfll Administration & Logistics DATE: 21 November 1952 naG : .ivision lDgistics ~~fJ SUDJECT: Sodium Pentothal '7 1. Below is information requested concerning the possible methods of neutralizing the effects of Sodium Pentothal. 2. The class of d..'"'llgs known as the "Central Nervous System Stinrulates" will, to a limited extent, counter-act the ef!ects of Sodium Pentothal. Some of these are: Benzedrine, Dexadrine, P•crotoxin, Caffeine Sodium Benzoate, and Strychnine. These drugs have, certain limitations howev~r, which more or less preclude their successful application in clandestine type Such limitations are as follows: activi~ies. a. The:r must be administered just before or just after receiving Sodium Pentothal. This would be difficult to accomplish as it is doubtful that the agent would have the necessary beforehand kn~~ledge of his treatment nor v~ ld he be allowed to administer himself during treatment. .\ b. Such dLTUgs would have to be secreted on the person and ad~nis­ tered (such as pills) externally. It is believed that a tho~ough search of the agent would disclose any such secreted drugs. c. A physician administering Sodium Pentothal would continue to inject Sodium Pentothal until the patient evidenced the desired re ., ...... action; therefore, it woulrt not be possible for the agent to consumP. enought Central Nervous System Stimulates to neutralize an excessive amount of Sodium Pentothal a."'ld still remain alive. ). Modern psychiatry regularly employs in therapy such tools as narcosynthysis which involves the use of truth such as Sodium se~~s Pentothal and Sodium Use of these drugs in psychiatric treatment ~tol. is limited as thP.y merei.y ena~le the ppysician and patient to explore more easily materiel in the forgotten unconscious of the patient; such treatment is usually long term therapy. Further, many psychiatrists ~~d criminologists have reported value received from the use of truth serums as oft<;n negative. The reason for this is that if the subject has exceptionally strong inhibitions certain material, truth concer~ing serums are not powerful enough to cause him to divulge the inhibited material. In view of forgoing, it is that if were th~ believ~d a~ents l.r ~J....Y.?t::s.ed_~n .!-!l_eir_cover_ ar.d_thP._s~c~r~_~y _of_such_cove.r, th.:lt would be exceedingly difficult to extract sensitive from info~ation 1h£m while under the influence of truth serums. - - .. -'!-: .... - .. "1. ' . -. -.. .. - 'P • ...-..· ._..,.: This document is a typed memorandum from the "Office of the Director of Administration & Logistics" dated November 21, 1952. It is marked with handwritten annotations in the top right corner, including a date "A/B, 1, 8/4" and a numerical "4". There are also handwritten numbers "65p" and "97" in the right margin. A significant portion of the document in the bottom right has been redacted. The memorandum discusses methods for neutralizing Sodium Pentothal and its use in psychiatric treatment and as a truth serum. While there are no photographs or diagrams, the document's layout and the presence of redactions suggest sensitive information is being conveyed. forgoing, it is that if were th~ believ~d a~ents l.r ~J....Y.?t::s.ed_~n .!-!l_eir_cover_ ar.d_thP._s~c~r~_~y _of_such_cove.r, th.:lt would be exceedingly difficult to extract sensitive from info~ation 1h£m while under the influence of truth serums. - - .. -'!-: .... - .. "1. ' . -. -.. .. - 'P • ...-..· ._..,.: .·. .. ...... . · , - , '. _., 4. It ~s recommended that the foregoing information not be accepted ~- . as fact, but that·a reauirement be presented OTS for a reasaarch project problem or neutralizing the effects or ~t~the trut~rums. ~I ADCS/MO has indicat.ed his willingness to aid .. in the G- preparation or such a requirement. 5. Your comments are requested concerning paragraph 4 above. "r. ... A / , .-'LP/bhd I· ---· - -- : . . - : ,_ '4: -- T , #0 ·-• .-.... ·-·,.:;::_ .-.- ~·· .......... -·- ···_ _ . . _,,-·'· ... _ H 220!)007. I. . \ t1l\i • • • • • 2217Y,17. I c. • lS c ; ~ .• · ; " · · · · • ~ · ' ' J " . ' . : ; " o ! .I ' J ' ~ ' ) ' 1 - ~ ~ · · ·o · - ' - "' · ' 7 • (J9 '" ': .,. J , . 1 ' "J ' ·i ·• ' 1< ;J : ~ '1 ' I 1 . ) • C. T...; 1'-\1,:~ 7~) ;[,·iJ.C.~.J ~,.,.,_,_J_J,__l.l;.r !:·.:1: 1-.. -~: ... ::J', lf 1_:• ~T .. ·.·. 1. (. ·~·.£.;..;! cnr,:~i' ~·-:!· .. ···.:,r:.n;;:. '::' :A:J.~17. iti'f ::.".~•n (J;;5'J :tn h50 ~ti TC:c I ' "'" ... '.'.t' ... " ' I '·. I' ../ .1. c r In:;!, .IP I'" I_ L:. :: '. ,: ~ I .'• ., ... i>U ..; J\r .I I /\. .. ur . ;f ;._.. irtn:·_,_,,:;,_tt,r; ,.._. r;'i)J.1.t"f~-.!; ·- ·. ~ .. r. .J ''-' ft r. .. ! ~' < ; ; \. •· ,1 \ I ' . .. . , , . "17!: r .... !',i]1. .: J;:J.:;: ·' ! , ' ·:-.-.-. A"/lf'no·· I J.~ • .\. ~ • ). ~ ~' _It,,; • I r-::::ii rm·: 2J/l..3JOZ 0 p y C 0 F 1 r. 0 i' y .. "I .: J;:J.:;: ·' ! , ' ·:-.-.-. A"/lf'no·· I J.~ • .\. ~ • ). ~ ~' _It,,; • I r-::::ii rm·: 2J/l..3JOZ 0 p y C 0 F 1 r. 0 i' y .. "I The image displays a typewritten document with handwritten annotations and redacted sections. There are two main handwritten annotations, both appearing as the letter "A," one in the upper left portion and another more towards the center. There are also several large, dark redacted areas, suggesting sensitive information has been blacked out. A handwritten initial "G" is present in the upper right, and the initials "LP/bhd" are written in the lower left. The document appears to be a formal communication, with paragraph numbering and a header possibly indicating a page number (-2-). The document is a declassified CIA memo that appears to be a request for information or action, likely related to MKUltra given its context. Handwritten annotations are present throughout the page, including a large "A/B I 17-3" in the upper right corner and a series of lettered and bulleted points. Redactions are visible in the middle of the page, obscuring specific text, and a dark, scribbled-out redaction dominates the lower right corner. There is also a distinct stamp-like marking for "COPY" in the lower portion of the page. The document's layout suggests it is a form or report with several fields for entries, including "A. TOP:" and "RSND TOT:". No photographs or diagrams are present.

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