Doc 0000144771

The image displays a vault door on the left side with a blue, glowing light emanating from it. To the right, white text on a black background states, "THE BLACK VAULT" in large, stylized lettering. Below this, smaller white text explains that the document was obtained from "The Black Vault, an online database of declassified government documents," specifically mentioning the "MKULTRA/Mind Control Collection" and providing a website URL. There are no photographs, handwritten annotations, stamps, forms, diagrams, tables, redactions, or visual evidence of experimental procedures present in this image. lo tO Chiot. PI.AnS 10 Ja.nunry 1952 AT!Il. I FROM ' ~l'BJrA:T a ALCOUl1L ATl~AGOlli:JTS '· /l 1. Rocontly I requoatad ---.-~:.:~.---, OSI, to provide the available intorlll".tion on nleohol llnto.&oniats nnd tho ef.t'ect of BcnEadrino, in particulnr.· l'"ne 1nitit\l atudiea indicato four posoiblo nrpro11chos to the probbm '17h1ch hnvo not baen oxl1.-~UDtivoly s tu.Jiod. n.. Uso of alcohol nnt~.r;onisto l~fora dr1n':in;,. 1. Don:odrin~ 2. Forvitin b. Adoorytion o.t' dcohol in the dir,ootivo trnct. 1. C~rconl 2. Alumin1.-~ r,ol proparntiono c. llonyY ont in_:_o r 3t:--rchco nnd C\IGO.r3 _..2£f_01:_0_!..11d ;·:hilo~inld.nc;.· d. Accolcrutod nlcohol oxidnti,u (oliminn·tion). •. 1. Enz~ adjuvo.nts, such na nicotinic o.oid • ... _ . · .L' 2. If it is nnticipntcd thnt o. propo.rn.tion in liq ' uid pill or G •-rr, cepaulo form should be provldod ror ~ uoo, _ _ . --. ha.o au1:.~ontod tho.t /j · rurthor rooeorch could 'bo int1ticn!:od at- · t'.nd culm.ina.tod quito ro.pidly to doter:-:U.ne tho ·moSlt c.t'.t'octivo t10dium This r-rork mir.ht 1 be conducted no pnrt o£ tJ1o "AflTICliU.KE" pror;,rn.":l • . 3. h G\'!T.nt".ry' of tho i~itinl t.;ochnical .t'1ndin;;s o.ro e.¥tttchcd for in!'orr..r.tion purpof:oo. It dooo not represont n.n c:-.:mnslvo ~~vcrnr;o of: tho sul>joot. Attnclu:vJntt Inoo:ticntion end Alcohol Aboorp:.lon and Antr.~.gonista . : ~ · . - . - ..-: . . . . . : . ~.. . .. . .. . . .~ : ..- ---·-.: ;..,- .. .. ;---.: -.-.· ---~_:-,, II" ·,. • ·•·•' ... .. •'•'''~J.;}.L." • '. -"-.r •.-• .. .. - In to:tion tl 0:1 rmd A1 c"ho l f· br.orp-t ion n~:l .~.n t!'.r,.,ni:: t;~ 1. Tho dor;roo ot intoxication is a i'unction or tho blood-o.lcohol lenl. Thia rolntioruship waa dotorminocl during the 1ncroa.s1nc tmd dacroo.sing ph.Rsoa or the aymptoz:w, Mel 1 t was aho.-m to bo o.pproximtol;:r. linear. · . 2. Tho a~· ·ponrcmco ot symptorno occurrod \';hen t;h? ··f'.ppcnrn."'lco tllroohold" l7nB o.tto.inod (0.31 to O.G~~ nlcohol/blood) • TI1o dionrpoarod rthon tho "disnPt'oo.ro.nco th.roohold'' (0. 36 to o. 75;~) 17c.s· roo.chod. . · : . '· 3. Attempts to minio.:~i:e tho 1ntox:l.ct\t1.vo oi'tocto rollowin~; the ingestion or alcohol havo bcum conco.ntratod upon the i'ollOlvinr. J:~och3ll1.cl!UJ. a •. Ab3orption fl.t tho fSO.Strio mucooa b. Acoeloration of tho oxi<W.tbn or alcohol by the lit-or. .,r c.. Roto.rdntitJn aooimill'ltion by tho colb of tho body (pnrticalr.rly cortic~l brain cells). d. Incronocd rnpidity or oxcrotion. or thoso. onlj" rooanrc:hos involvinr, tho tiro t;. The document is a declassified memorandum with typed text and some handwritten annotations. At the top right, there's a handwritten annotation, "A/B, I, 64, 24". A large "A" is written in the margin next to the introductory paragraph and another "A" next to item 1. A circled "B" with some illegible scribbles to its left appears next to item 2, with an arrow pointing to the text. The document is typed and appears to be a standard business memo format, with fields such as "TO:", "FROM:", and "SUBJECT:". No photographs, diagrams, stamps, or redactions are visible. bcum conco.ntratod upon the i'ollOlvinr. J:~och3ll1.cl!UJ. a •. Ab3orption fl.t tho fSO.Strio mucooa b. Acoeloration of tho oxi<W.tbn or alcohol by the lit-or. .,r c.. Roto.rdntitJn aooimill'ltion by tho colb of tho body (pnrticalr.rly cortic~l brain cells). d. Incronocd rnpidity or oxcrotion. or thoso. onlj" rooanrc:hos involvinr, tho tiro t;. tr;o h!\ve provon nt o.ll fruitful and studies of adsorption tnvo boon moot thorouv~ly considered. 4. Some or ~1e·o~rliost ~ork on tho absorption or Rloohol (1916) - oc· shows that a.boorption is prolonr;ed and avpeo.rs later \Vhon the e.lcohol 1s to.ken after food. The sa.:::o :~rorkors round that tho intnke or rood with alcohol not on11 tiolnyod absor~t1on but thnt tl1o nbnorpti?n novar reachod vo.lucu round ;~hon c.lcohol •·tns r;ivon on r..n e:r.pt"J otorno.ch. It io clni.":ll)d th.'\t tho!.~ din npponrollOO or alcohol is tluo in p~rt; to ~:ho nlcohol novor b~in;; nbsorbQd ao ouch. Tha alr.~ntc o.ocribo this to 1.;!10 o.lcohol boinr; bol.'l11<v to some cons ti tuont pnrts or tho rood such n.s protoinD end r:u:d.no-t\cids. Thio theory tit d~lution aee:ns to be conf'inned since the blood-alcohol lcvol nriea with the qua.nti ty or rood 1n&oeted. • 5. !Joro &orr.tmo to t.~e prnblam nt hMd than the ph~•siolor;1cnl mochnni::m Of nbcorption io thO CCnrch f~r 11 SpoCiric GUbDt:lnCO to lOG:lOn ti:O nb:::orption l'l\tD nnd henco lO".TOr the blo'ld•nlcohol lOVOlo Of ':ho limited nt.u:ibor or foods tocsted, ~ hnd t.~o ~n.tect orroct. G. A'ttompt:J to rod~tct!) int o:r.icr.t.:\.on ni th dn~r.;c ns llt!.ll:t·, nir.1 at !\!1 incr·JMO in the rnto of oxidation or tho nlcoh?l in tho liv~r. Thio rt\t.o io ~otnblioMd 'by nn enzyme procO:l:J in tho liV 'Dr "M"hich cr..n b~ influoncou 11-J dnt:;s. Tho · cnr.ymo procooo is n nicotinic ncid-riboflo.vin oy:lt.ci:l thnt ic rcs·ponoiblo for tho o:dd!ltion or nlcohol to ncotnldohyclc nnd aldoltydo-mutn~c in tJ1o o~idation or ncotnldohydo to o.cotio l'.cid. 7. Dr'.lcn ~·tllich nccolornto t\1cohol m-,·to.bolis:n inclu11G n.lru1ino n.nd Lmmlin c;lucoco. It io clo.i:rcd tho.t inG\llin retd b:lulin-frJo f!'.ncroo.tie o;ctr~ct aro oo;. cnpnblo of incroo.sin~ the ro.ta of alcohol mta.boliem o.pprox~toly in thorapoutio dooea 1n man. - ' \' f ,._. , . . -.,~ ·.:._.-..,.-.~ }-. u. tm tono:Uo r.lru1::3 ntlCh n:J rv.!.r'ln~rr:!.c l:l~1bo !;r.:~c~::; lil:o n~'l~h<J t.--.: :tino sulfnto (l;on:ol.!rlt:o) o.re f:>tlZl(l to bo rl'.lt't offootl.-n.' It h!'.O br.o:: t;lvon in f'~:tfluntn roncin~ !'roa 0.5 to 0.7 r.;r~.ru:/!dlo-body noicht to 17 subjoot:J nnd !'O'.md t;o ahem a definite inhibiting ettoct rJhich wae The document appears to be a declassified page from a scientific or research paper, potentially related to the effects of alcohol. It consists entirely of typed text, formatted into numbered points and sub-points. There are no images, photographs, handwritten notes, stamps, or redactions visible on the page. The text discusses the degree of intoxication, alcohol absorption, and attempts to minimize its effects, along with mention of drugs that might accelerate alcohol metabolism. The overall visual presentation is that of a standard, unadorned textual document. -.,~ ·.:._.-..,.-.~ }-. u. tm tono:Uo r.lru1::3 ntlCh n:J rv.!.r'ln~rr:!.c l:l~1bo !;r.:~c~::; lil:o n~'l~h<J t.--.: :tino sulfnto (l;on:ol.!rlt:o) o.re f:>tlZl(l to bo rl'.lt't offootl.-n.' It h!'.O br.o:: t;lvon in f'~:tfluntn roncin~ !'roa 0.5 to 0.7 r.;r~.ru:/!dlo-body noicht to 17 subjoot:J nnd !'O'.md t;o ahem a definite inhibiting ettoct rJhich wae t;reateot t'.tter 30 ::dnu~s but thon d.1mi.nlshed. The~ dru& ,~o r:;ivon both ornlly onri 1ntrnvonously w1 '\ill oonnistent nGul ta that r.oro rchtod dlroctly tu1d o.:r:clu:Jivdly to the !l!'!lount or r::ophotnmino r,ivon. ~·nrr.~:rinc, ac'l.ronnlin ~.nd n tropino oulfa.to ~'fora e. lao too tod ond folm.d to bo orroctiv o in thl) ordor lis tad. ,. f I ~-i •. ·I - ... . .. , 'I I i . . ...... ~. ·• I·.-;." ..•f" .: . • .... -., .... ' .. . .· -..-.....· -y. ... . . This page contains a typed document with a single numbered item describing the effect of autonomic drugs tested on subjects. There are no photographs, handwriting, stamps, forms, diagrams, or tables. Several vertical black bars are present on the left margin, and scattered dark dots and smudges are visible throughout the page, consistent with the aging of the document and potential scanning artifacts. Some portions of the text are slightly faded or blurred, but no deliberate redactions are apparent.