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This CIA document from April 1946, concerning "Truth Drug (T.D.)", describes a liquid acetate preparation derived from cannabis indica (marijuana or hashish) that is tasteless, odorless, and colorless, and details its preparation, analysis difficulty, and dosage.

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' ~ .L/ (... '(/ '].J I 5 April 1946 fiJ::.tOit\JTDU:.t FOR Till-~ FILE: SUBJE.CT: Truth Drue (T.D.) '· ----=T_he following lr.for:nation was passed out by ·· ':-: -.. "7;) .: ::·':·> :~~;:::..,,.:,--,,,~.-:.:_:.·:.';.·'~;~·:-: ·-~~~S~~~ dis~ussionsa. tl:,., ... . . on 30 &ld 31 JanuarJ 1946. This memtrand~~ should be re~d in conjunct ion wi ti1 the notes prepared by on I:. his subject, and wi ~h tite report of the OSS board whtch conc:hlcted linical tes t.s, cop l.es of ;"h ich are a Ltached. A. T.1F. DfiUG: 1. The Drt~g is a liquid acetate preparation or cannioos indicia (mari.iuana or hashish). It is prepared only hy che:nts ts of the, ·and is produced as an otl v/hich has no taste, odor or colcr. TI1c preparation in an involvE"d r:rocesG, done prL'1Cipally in tc1o Laborotor<J. There is no rea~on to believe that any other nation or gr,.,·tp i::; f.:1.m.Lliar Yll ~h the prep~ rat-ton :mel uso of ~lis parti.c11lar c.lrug •. This drug ls almost i:npo::;sihle to anal::ze, and, for this reason, there .. would be little· danr_;er of aomjlro:nise if S.:tMrles were to be · obtained by any unfriendly a~,;ency. This oil ls not mi~cible in any liquid except alcohol or s irnil:!r pr'JdllC t, nnrl ~hen onl:r partiall:;. Accordinr;ly, it cannot nor.:tally be u:::ed in a drink as it retains its r,lobul;J.r:fon, and bei.n~ he11vier t..1~u: 1·mter will olnk to Lhe bottom. If vigorously sho.ken in a liquid, it will scpo.rate into tiny droplets and roril<lin in a ::; tate of visible O'tspen::;ion ~,nt.il the 11roplet.s gr.'ldu~ly sink. The l::; nO"N e~orimenting with a t~nctur!e wi1lch vrill allcw proper proportions of !:.he drug to l>e ins~rt.ed into a drink. 1. At the pre:~en t Lime the oil is prep;lr~d b;,· thr, /) in n:•tpules of 3 c. c. lnasrnuch as Lile r:ia:'J.m>tm dose is .03 c.c. the present amp11les are too larGe for our use, and it should be sugcestetl that a:apules or • 5 c. c. cnpaci ty 'be pre pared. The nonnal minirm.1m dosa.r.e is.Ol c. c. In Ciny case, it . ... -· ~ .... .. ·-; , :··- .. .... · ~-~-·-.. ·--.- ··""::, ......· :~ ..... '•· . -. , . . . . .. . ., . ·., . .. --· .. \ ----------------------------------------------------------·--- - 2 - • has been found that the Drug must bo ins:estcd in order- to be effective.. The image is a digital representation of a document's title page, not a declassified CIA document with experimental content. On the left, a graphic depicts a detailed, metallic vault door, symbolizing security and hidden information. To the right, "THE BLACK VAULT" is prominently displayed in a stylized, white font with a blue neon-like glow. Below this title, white text explains that the document was obtained from The Black Vault, an online database of declassified government documents, specifically mentioning the MKULTRA/Mind Control Collection and providing a URL for access. There are no photographs, handwritten notes, signatures, official stamps, forms, diagrams, tables, redactions, or visual evidence of experimental procedures or facilities on this page. .. ·-; , :··- .. .... · ~-~-·-.. ·--.- ··""::, ......· :~ ..... '•· . -. , . . . . .. . ., . ·., . .. --· .. \ ----------------------------------------------------------·--- - 2 - • has been found that the Drug must bo ins:estcd in order- to be effective.. This can be clone either by eat.inr,, ns 5.n candy n or food, or b;: inhalation, b:r meant~ or a cic;arette. has been found that. the cigarette rnP.thod generally f.;lves a quicker effect. In eiLher 'Ca::;e the drug is inserted in to the· food or tabncco by mea."l:; of a hypodennic syrinBe• In Ure =ca::re of a '· cigarette, the noecne should be thrust into the cic:~.rett.e along its axis for about cne inch. S,lovrly withdrar.inc the needle, the plunger should bo slC\Tly depressed so th:J.t the drug is deposit-ed evenly along this portion of tho cit;aret.te. Care muot be tal~cn to avoid the druc 1seepina thiT'Uf:.h ::1::1d 5taining t!1o paper. Thi~ procedure shoult3 ba followed r.Lth bol.h ~n·J:::: of t:te cipratta in order to i1:Jure t:at the :!linimum do::acc is ab~orbed. It is r-bvious that tite S'Uol:inr: !Jabi ts of nn in- di v'i.du~ will lart;ely detcrmJ.ne the a"IOUnt or the drug o.hich he inhales. Tho opera tor should have ob3erved these habits in order that, an adequate, but not (!Xcessivc, dosac;o be insu:-ed. In o!..'ier ca:::;es, -the drur; cnn be in.}ect~d into any t:n'e of rood, such as mashed pot.atoeo, butter, s~addrcssing, or in sue~ Lilin{;s as candy. By t·hls !llethod a clo::~e:" check c:m be t;~.ainta.i.n"!d on the ac l.ual a:nount or t.lle dro:tg which is in;.~c::; ~~cd. 1. The cpcr.:.':.0r c:u1 lo:~l: f<,r '1 rc~~tir:>n fru:n ~10. cicar-oLto ;;'!Othod in nboul:,'l) r:U.nu!ioG, und fl'O!U Ulo fooJ nct.:1cd ln about. 0110 il.:lll' itonr :,c 4) ;!'l.:.nutc~. TitC:3C ~rc not. alrm~·s ucpt3rldablc rules. ~10 :;_i.:!lo ci! rcacLion \·;!.11 cli.ffcr wll.;!l eneh l'or:;on, and it depcnJ:; c~,;n::;!.dcrauly on the pilyn:i.cru. crJwi.Lt.ion of ::.:1c ::;ubjoc~, tite a.~':"-.lllti of ft:··,d or li<pot· iw ha:; alrct~t!y ccLS11":1oJ., ti10 lcnr:th or t.i:':le 5 tnce iLls l:.w t. X~tl, c t.c. Til9 opor::l Lor _.,'ll11<.t no:": t. bnccme b~patic:1t. lf the effect iG ~:i..r.m in ac:;on.rinr;. C"lro !':iu:;t 1.:•c t~~cn not t.o n(bin:_~t.or 'lrmccP.:;::;ar:· <3.;;'101\nt.s .of ':.'10 :.1!"'li! "u~causc, alt::our;:t ~m tlr,lG ;-:ill no~. 11\.i:.:re t.:M:) E"'Jbjer.li, 3.'. ;.-L].l.;_Jn·o·ua'bly cau::;e him t.o lone consclousnc:.n in t;to nu.:.:~e ra:J.tlllt;;l" ·~:; ono ..-.ilO ld complc tcly This document is a declassified memorandum with official stamps and handwritten annotations. The top right corner features a handwritten annotation "FB, I, 64, 3.3" and what appears to be a date stamp fragment with "32-1". The document also contains handwritten marginalia in the left margin, appearing as cursive letters and numbers. Some text within the document is obscured by small, solid black redaction marks. The page is primarily text-based, with no photographs, diagrams, or evidence of specific experimental procedures, equipment, or facilities directly visible. _.,'ll11<.t no:": t. bnccme b~patic:1t. lf the effect iG ~:i..r.m in ac:;on.rinr;. C"lro !':iu:;t 1.:•c t~~cn not t.o n(bin:_~t.or 'lrmccP.:;::;ar:· <3.;;'101\nt.s .of ':.'10 :.1!"'li! "u~causc, alt::our;:t ~m tlr,lG ;-:ill no~. 11\.i:.:re t.:M:) E"'Jbjer.li, 3.'. ;.-L].l.;_Jn·o·ua'bly cau::;e him t.o lone consclousnc:.n in t;to nu.:.:~e ra:J.tlllt;;l" ·~:; ono ..-.ilO ld complc tcly dL.,_mk, and no further q •es tionin: ~ .,, ill lJFJ ptis~;ib~c. An adn;ni:::; ,I''-!!,icn •Jf 1ro:n .01 c.c. t:.o .OJ c.c. v;lll r:u:J~r;J.}_2.:; llilVc an effect l<.i:> t.in•; aiyHJ t. onn !l•.'ur. !lowovo1·, · t ~. • ;_ .: ; • lV•J been ncces:;ar;,;- for tho arir:UnL~; t.l·<lti.l)n t.o Lul·;o jrlace <nor 2 or J hoars. Tilorofore, it. is <:!S:.H:nl-i.:ll ti1.1.:, ;_:n op•;)ra:,'L('n of '}1~:; l:lnd not. be at.Le11ptod u·•lc:.s there in rca:Jon:.ll.llt~ cor~aint_; ~~l.:.Lt there \7Ul bo no interruption over a period of ocvcral hour3. • I . ·• ~,..- -. - 'r... - . · . ._ __ ,,. :. ~ . .\ . . !" - .• - . · . r : . . ,. . .. ; .. . . ,·. - . . - : . , . .. -.... :. ·. ..,., -:- .. ... . -- - - '! · . • u 2. Tho of!ocw of tho drut; ara similar in ::nny wa:ls .. to tho o!foct.s produced b'J alcohol. TI1e brain r<nct::. as ' vthm intoxicated, but. no dolu::doins or h<llucinat.ions nro pl"'tlnced ~'lS i.e t?1c ca:>c tn ".. he u::o of dra~S t;llCh 0.::3 O~~p0la-:tlnc. 1'i1o drn3 appears to rela:: a.ll in.'1ihi ~.ions and !,o deaden ti1a :J.reu:::; or ~W brain T.~ticil :;ovorn an :i..ndividlt.ll':J di!-!cr~tion and c:rt t.l'J!'l. It .:llr:o n'cccntua to:; the scn:;c:; :tnJ 'l!.'l:=os 1!~:\hl.fe~t i!n:f.. ul.ront; ch·'lractcri~t.ics o! ~ll) lndl'vidu.:~.l. Sexu;U irthibi:-.ions · are lcr.\"cr~d, a.'1d t,;1c scr."'ll o.C' hu"lcr b accent,Jnted to !:.he p':>int "Yjhero any o t.l t.P.'llell t or si tHil tit)!'\ can boc~me ex+.rc~ol:r funny tc> t;1c :n:l·jcct.. On t.ha C'lt.hor h:md n person's unpJ.c:1.:::ant cha.r:lct·crlsLlcs m:1:: abo 'te l•atr;hto:1od. It m:w bo f:t.J.t.cd t.:l3 t, cem:ral:!.y :.::-=·•i· L"lt;;, th~ r~.;ct.l.cn TiilJ. be cr.c cf r:-r~:~t. t:r. loq\l'L!~ 1-~y a:ul hil;'lri ). In all casn:; a !JrRr•:q•ti::;i ~.n for t:·.e e ffcc ''i v•.l US'J of this drur: is U19 creation cf :1 fri.cnrlly, ·~:r:niXJ.th~ti.-:, i:lfnrmal l''l::l is for a discu::;~tcn, ~1hich ohould extend oYer .'l ?Cri')d of sevcr:.l hc. . urs. !li ::1u~t. not. ba unad on e hostile) The document contains typed text on a standard letter-sized page, numbered "2" at the top center. There are two vertical black lines running down the left margin, suggesting this page might be part of a larger bound document or filing system. A few faint dots and smudges are scattered across the page, but there are no photographs, handwritten annotations, official stamps, forms, diagrams, tables, or redactions. The visual content is limited to the typed text, which details methods of drug administration and observed effects. This document is a typed page of text, numbered "-4-", from what appears to be a report or research paper. There are no photographs, handwritten annotations, stamps, forms, diagrams, tables, or specific visual evidence of experimental procedures. The text discusses the effects of a drug and its practical applications, citing an example involving a German submarine commander. There are a few dark, thin horizontal lines and one vertical line on the left margin which appear to be part of the document's formatting or a binding. In all cases a prerequisite for the effective use of this drug is the creation of a friendly, non-authoritative, informal atmosphere for a discussion, which should extend over a period of several hours. It must not be used on a hostile subject but rather employed on a subject who is suspicious, but not hostile. It was proven advantageous to spend considerable time during previous meetings and deliberations before initiating about the proper environment for the use of this drug. Some cases of its use follow. As examples of the foregoing, the story was told of a visit to a prisoner of war camp in Virginia where men of top-notch German military prisoners were kept for interrogation. One German in particular, Commander Werner, who was considered an outstanding man in his field, had been the sole survivor of his submarine sinking and it was thought he could yield valuable information concerning (1) the depth to which the submarine could go with safety, and (2) the most favorable operational depth of submarine crew. Both of these items were of paramount interest to our staff at this time. An attempt was made to obtain this information from the commander of the submarine as he was extremely wary. At the time of the visit in question the commander was invited over to the officers' club for a few social drinks, which were more or less war-time. After a few drinks and some conversation, it could be seen that while he would talk freely on most all matters, he was well aware of the fact that an attempt might be made to obtain information from him. This opportunity was found to give him a drink which had been located and after approximately half an hour had passed from the first administration, one of the company, in a roundabout and innocent manner, lead up to the question of maximum depth of the submarine. cd fra-:~ •lte firs!. ~ubln.i.s t-ration, one of the c~mpany, in ~ round-:J.l.'lOtrt a.."lcl .. in."lOCent l:l.:lnner, lead Up to tha flUCStion Of 'll3xi:r.urn do[.th Of the submarine • . :· . · .-. - - ~ - ~:.. . . . -,. -._-, _-·_· 'l>,.. l_ - '·.· --.... ..~- .. •· .., . .. . . .. . .. . . .. . ' . . . . -~ .. ~. ! .• ~ . · . : ... ·- . . . - - ...... 4 ·-~. ..... ....... _.·_ .· •· -5- The commander, although at this time definitely under the effects of the drug, was still \H!.ry and indicated he-would ; .... not give on this point. Some time after !~ormation later~ two more ciGarettes had been cons•.uned, tho talk was led around to morale and he freely conversed about the loworing con~ral of morale of German aubnmrine personnel. no infor IIo~·,evor, mation was over concernins depth. ~btninod maxi~ '· b. Another is thnt of a notorious dope peddler ca~o and racketeer in new York.City who was well-known to the operator from his days of law enforcement work. 'Ihe dope ~ I peddler was telephoned and asked to cor::e to see the operator who described as beinc connected with hirr~olf secl'et c;overnment work and who wan in a to cive po~1t1on the elope peddlor an opportunity to help his country in tho \"Jar. Despite the cb.aractor of the peddler, he evidently harbored some feelirlt;s of po. triotism and present od hirns elf when lt was explained that it was thout;ht hi:J connections in Sicily could be used for espionage purposes. Conversation • along tbls line was carried on for 3ome ti::r.e aau no reference " was made to any illegal activities of the dope peddler. hlthough. peddler did not drink 11e was per the.-~dope liqu~r, suaded to take just one liqueur to keep the operator "compan':T"• Also durinG tho time, three loaded cir;a~·ettes hod been given t::> him at diffE>rcnt The effect was tir.1e::~. q: ite rapid and about 20 minutes nfter the thir.d clr;nrette, the peddler· told freely of the nany illegal activities in which he had peen and wan then engaged conceming the ·. smuggling of He then many of his narcotics~ al~o n~rned associates end officials who were also involved in this- " • activity, althJugh he was well aware thot the The document is a typed page of text, likely from a report. There is a page number "-5-" at the top center. The text is black ink on white paper, with some minor smudging and ink splatters visible in the margins and throughout the text. There are no images, stamps, or handwritten annotations on this page. Three vertical lines are present on the left side of the page, possibly indicating an area where pages were bound. the peddler· told freely of the nany illegal activities in which he had peen and wan then engaged conceming the ·. smuggling of He then many of his narcotics~ al~o n~rned associates end officials who were also involved in this- " • activity, althJugh he was well aware thot the person to whon he was to lking was, and m1cht be in the future, connected with law enf9rcomont activity. A 11 ttle b. tor tho ped,Jler complained of faelinr; very licht-hes.dcd, thoush he hnd too much liquor. a~; l~o.d He dis curded this 13:;Jeplo.na tion, hov:cver, boca. uSe he hnd hnd only one drinlc. lie did s to. te that he had. been hnvinc;. e little trouble wl th his d1e;cst1on o.nd ho hnd not•' eaten for approximately 24 hours. The operator to cover up this situation convinced hin that the one liqueur on an empty stomach and his fastinc; hnu made hir. sick o.ncl suscep tible to the alcoholic Hu ac ceptEJd oxplo.oo tion. fume~. ~:-:.iz c. Another case wao one which illustuated tho rule - that a friendly basis must first be established and that suspicion must be allayed: This case involved the ·;. questioning of appro:;Jeimately 30 army officerD in tho space of one dsy. All of the officers were suspected of belng and the interview here being held to try to Co~~unist ·· ~ ' -- ~ ---~ . _ ... . 11 . , .. _ .. _ • -•· · .,..-_ ' ,, ............... _ .... ·.., ...... .· •, ., · ...... · : ,• ; . ....... --------------------------------------------- ----- -6- establish the eu:Jp1cion. It should be notctl that beca\).ne .. - J of the speed with which the interrosations were carried out, no mutuality of feelinG could be first ez tabl1shcd, o.'nd also because most of the man were tn fact Comnunizts and were suspicious, thci r fenrs concerning the quest 1onins ;;ere not quieted. iievertheless, the drug administered in. wn~ ciGarettes and five or the thirty, CJVen ttndCI' the adxerse comli tiono, gave full informs tion concern inS their communist , affiliations. 4. It must be remembered that when the effects of the :.. --1 drug wear off, it is probable that the oubject will be completely aware d: the fer:t that he talked freely e.ncl wn~ ~ousibly ind13crcet. For this rAoscn, it is desirable where ever to the une of The document is a typed page with a dark border on the left side, suggesting it might have been part of a bound report. There is a page number "6" printed near the top center. No photographs, diagrams, stamps, or handwritten annotations are visible. There are a few small, black marks that could be ink blots or minor printing imperfections. The content focuses on the effects and handling of a drug, referencing its administration in cigarettes and its potential use in conjunction with liquor. There are no visible redactions or obscured content. The image is a scanned document page with typed text and handwritten annotations. The text is in black ink, with some lines appearing slightly faded. There are no photographs, diagrams, official stamps, forms, or tables visible. One handwritten annotation appears in the left margin, in blue ink, reading "C+49". Another handwritten annotation is in the bottom right corner, also in blue ink, consisting of a single character resembling the Greek letter "zeta", or a stylized "2". There are no obvious redactions or obscured content. affiliations. 4. It must be remembered that when the effects of the :.. --1 drug wear off, it is probable that the oubject will be completely aware d: the fer:t that he talked freely e.ncl wn~ ~ousibly ind13crcet. For this rAoscn, it is desirable where ever to the une of the druc with po:::~1iblo a~::ociatc liquor, in order that th1~ effect will not arouse ~u~~lcion. Neverth€'le:::s, it cohould c.lso be rei:tcmbercd tho. t the subject subcequontly may bo c~pcctctl to feel r~orsc, embarraosmcnt or alam over tllinr;::: he kn0".7::l he l:ns sale!. r.xtrcme reaction::: in such ovont.could be~ a) flisht; b) suicide, or c) - personal dor.ger for tho operator. It is po!!sible that roaction:J of -,thi:J type r.1ic;ht outwoight tho beneflte which mieht be sained bJ the use or the clrug. D. c:>vr:n 1. Inc.::Jnuch os the· crut;, syrin:e, alcohol' fci' cleaninG, are all contained in a kit, tr..c posocs::or of ::~uch e. kit I:IUS.t hnve a logival re~::;on ~or its prcscnc~ tn his effect::~ .... The person inwh::>se.care the druG and tho equipr.:1mt i~ entrustocl ... , sl1ould be covered by a story, preferably backed =J documentary rnf,lclic,ll evidence, which lndicatos thllt llc 1::> roceivint; insulin shot::J, self ndmini::Jtored, allergy shot:, or something ... similar. He ::Jhould be prepared to demonstrate his cover e tory if the occs:; ion derumds. E. UISCELLAirEJU.3 1. Tests hnvo sho~m that the dr..._1.1: m'ly. r<'!main -"potent in a cigarette for n couplP of W(-'tlkn snd ln one coso 1 t was found that considerable rencti.,n \rn3 cnu~cd t"j· o cir;or(>~te in ~1ich tho druc had been introduced approxin3tely six months before. f,= a r_;cnr•ral rule., ~he dr,;:: _:tould koep (''!en better in food unles~ tho food ltsolf wPre to spoil. .. 2. Possension of the druG is contrary to Federal lnw, ~- .• --. .. : ..... : .... ··'~ ",? .".· =-- -~--·~ -7- .. and a spacial license, obtainable from the Bu.reau of ·. narcotics is necessary to ma~e leeal its possession. This fac't mo.y be u~ed t':l rrevent thEl reoten';i':ln of this drug by per::~ons n':lt in the employ of the Government and who should have to the drug. ~o acces~ 3. The s;rrin~e must be graduated in .01 c·c. This is very important in order to mcnsurc the doooco accurotoly. A recommended model is th:1t called the tuberculin oyrince, which is eo graduated and which haa a capacity The document is a typed page with handwritten annotations and a stamp. The typed text describes a 1942 project to develop a truth-inducing drug, mentioning prominent psychiatrists, biochemists, and the OSS Research and Development Department. Handwritten annotations include a numerical code in the top right corner of the page: "A/B, 2, 64, 35". There is also a handwritten "A" in the left margin, and a symbol resembling an "R" with an underline in the bottom left. A horizontal line appears below much of the typed text, suggesting it might be part of a form or a section being highlighted. The document appears to be a formal report or memo, evidenced by the typed text and the handwritten referencing marks. of the Government and who should have to the drug. ~o acces~ 3. The s;rrin~e must be graduated in .01 c·c. This is very important in order to mcnsurc the doooco accurotoly. A recommended model is th:1t called the tuberculin oyrince, which is eo graduated and which haa a capacity of .25 cc. After each use the r:yrlnGe sh:mld be washed O'..lt ;vitb alcohol to prevent cumming. 1be ~mpules containinc tho drug are now packed in 3 cc too :-::uci:, crmtainer:~. Thi~ 1:~ and e. • 5 cc or :JmP.ller ampule ~h:')uld ':le <lccnel-:>pcd to our rF~q'lest. The entire set, tncl'ldlns cover eq1.1ip.ent should QB oropared in a small nedicnl kit. , sh-:w1d "Jr; ~-:>ntacted by, .as a nourco of the drug and the equipment. 4. Regarding knowled~of this drus, it a eems that a. /) small number 'uf people in and~ nr~ awnra of its The drug def1ea all but the most expert · exist~nce. ~nc senrchin:.; nnnlynis ,qnd for practical purposen can be considerP.d annlysis. be~;ond --------~----~--------- : 1, ·,7-.,.·' ~- - _.','·. . , _::··:::';.'.e..;. ......- ."':':...,. ~ - c_: ~ : - . · : · . · .·. .::...;. .. , -:·_ .......... •• '.•-"":"-· - -.. ~... · 7. 0 : -..F :..-.-•. ·,·.·. --_\ ... --..·- •.- ·-,.·- :<. &. ..:....·. .,. .•· .-J-.~- ... ·~- ...- ·..,.._ -..- -...· ,• ..•. ...... _ _ -1 • ..,_ -·' ··--.. ·. ------------------·----·······-··········~------·····---···· .. •. . ------ ,. In the Sprln? of 1042 tJenoral Donovan assembled a '· sroup to inquire into the po~:slbllitic::J of devel"opinc F.\ . drug which. would have the cho.racteristic·of causing a ·• subject· to whom 1 t wo.s o.drninistored to tell the truth about matter:. where it would l.le contro.r:r to tho int.crcr.t.3 of subject. Pro~inent psych1o.trists, biochemists, ot~., ;1 collaborated undor the dir~ctinn of • -of Research and Development Department of 0~3 in nn attempt to produce such o>drug •. It was allesed that the Russians had such n subs t;a.nce nnu thn t the German:> nl~o err:ployP.d o. c.!ru,s in connection with r.he 1nterrocation of prlnonC'~ or. war •. ... This group made extensi~e reaearch on all possible druci including scopalBl!lin~, barbltuatea, peyote,· etc., nnd found of these subntancoo. to be . for vorlous rnasons. n~r~ . so.tisfnctor~ One C.cfec t VIas the production of hnluc1nn tLms, pnrticularl:r manifestf:d ln thn une of scopular:li!le. 7 T:•e cortr.~ttt.;ee The document is a typed page with several handwritten annotations. The text discusses attempts to inject a substance into a room and the effectiveness of different methods, including a "cigarette method." There are four handwritten marks (likely identifiers for different experiments or points) labeled "A" and "B" preceding blocks of text. Additionally, there are several underlined portions of text and a lengthy, thick black line drawn near the bottom of the page, suggesting potential emphasis or data points. No images, stamps, forms, diagrams, tables, or clear redactions are visible. war. This group made extensive research on all possible drugs including scopolamine, barbiturates, peyote, etc., and found many of these substances to be unsatisfactory for various reasons. One effect was the production of hallucinations, particularly manifested in the use of scopolamine. The committee finally decided that the most practical substance available was a derivative of cannabis indica (marihuana or hashish). Chemists developed an extract of this substance which represents the active ingredients and this is the "drug" now available. Most of the experiment was first carried out by technical personnel. Then on the Planning Staff. Attempts were made to inject the substance into a room in a spray, but this was unsatisfactory because the carrying agent was irritating to throat and eyes. The cigarette method was then extensively used with some success, except that it was found dosage could not be controlled. Later, [redacted] and myself obtained the importance of the same drug. Extensive experiments with a group of personnel on the various forms of administration, the results of which seemed to indicate internal administration was the most satisfactory. Numerous field experiments were carried out by the Military in conjunction with the project under personnel direction with some success. Some success was had on projects undertaken on behalf of the [redacted]. It was found that the greatest success was achieved when an opportunity was afforded to get the "target" in such a fashion as to lull the suspicions of the subject that he might be the object of interrogation. It was used in conjunction with formal interrogations with little or no results. It was used in conjunction with informal "power" interrogations where some degree of "coercing" technique could be applied, with good results. A drug or drugs that would induce the betraying of secret information. On April 1, 1944, the group began work on the The document appears to be a declassified report page. At the top right corner, there is a handwritten annotation with numbers and letters. The center of the page contains the heading "REPORT" and a line of text that reads "IVISTIGATION OF USE OF TD IN INTERROGATION" which is underlined. Below this, there is another line of text stating "With the technical assistance of" followed by another underlined space. There are no photographs, diagrams, stamps, or tables visible on this page. The rest of the page is mostly blank with some scattered marks and specks that appear to be part of the original document's condition or printing. ... An drug or drugs that would induce the betrayal of secret information. On April 1, 1947, the group began work on the project known as TD, is effective in extracting information during interrogation of individuals who are to hold it reluctant. Soon after the experiment was initiated, it did extent on the personality and motivational of the subject being interrogated. The investigation was to be broadened to include study of the drug in relation to reliability and situation, General Plan Personnel of the Office of Strategic Services who had information of a confidential or secret nature, were to be interrogated before and after the administration of TD, to determine how much of this information they could be induced to reveal. If more information could be obtained while the individual was under the influence of TD than at other times, TD could be considered an effective agent in interrogation. In order to determine the relation of personality to the effects of TD, the personality of each subject of psychological tests and psychiatric interview. Subjects Four subjects were used in the experiment, of whom Office of Strategic Services. They had been members for several years, and had performed duties of various degrees of importance and responsibility. All of the other men except two were present without psychological testing. The tested men and all of the officers had been given strict instructions before submitting to all experiment. This submission consisted of instructions had performed and that they were not to discuss the stress series of psychological instruments were administered to each subject. oi'fic<~r:> hutl ueen ~~ivcn :::trict ln::;tr\,;.ctl.m:: l.:cfoJ'• :;u'.;nj.ttinc to ~:ll1 c;~pnrlmo:nt. 'l'hi~ 11b1•cif.tnr:" con:;i::~t;ol1 of .tn:;~ructions . hod per fol'mEu und 2) tlln t they ·:w'!:e n:J !; 1;:) cii ~ul.~~o tLl:::: cu. s tre:-: r. 11. sorie~ os· p:3ycho1J.;lcnl l'nt;lllL~ lnsl;rUr.lcnts wn: ' J, ndm1n1::;tored to ench ~ul::ject. Tho r~:sults of these tocethor with a. pjchintric intor•:iow wore usod. to deter.:1lnc the --· .... " ... - ......... ~ · - .... -.. -·- ...... ~. ' --- ' -3-. individual's structure. The instruments we-re foll~wing ... ~ used: 1..... Rorschach ·TNJt 111 CO~"nell li.ldO:t 3. Cornell :;oru forrJ ' I • • 4. Goodonouch Drnvzin,£;-n-man-tcst 5. Self llatlnw to:1t 6. ·:·lork Intores\; Blank 7. P-S D:poricncc Dlnnk a. 1nt.ol"Vio•7 P~:;ch1ntr1c Each 1ruJ1vlCi.tal \1ns su:_,j~ctou to ~:~1 intcrrosntion in o.ntttorr.pt to t:ll~co·1or wi1nt clutlcn ho hnu pcrforr-,cd. Intorro cntlon Cnrriod.out in infornnl atmoDphcrn .b efore, - ">1Dtl D.ll nftc:r. clurtnr; nnd thh ednlnistratlon of TD lntorr'J(:D. tion WA~: l't:COl'Jol1 by ''lnnn~ Of 0. U~.Ctr.phone !:. ;'eclal l:lcctJ•icor~ Rocor·uin~~-nop1~od';l .... 1n:, ~·nchfne •• Tho.-· - . subject VIas not &'f!nre \1~ t l'lis converfln tt ..,n vzns bf'\inc recorded. .. .... -~- These rcco:-uin:;n forr.1ccl n ncrmnnont; rncor~l o!' tho rs:rch1o.tr1c or l••tr.l"'·.ricw ond of tlon tho :: nljectn, b:r nenno tlH~ 1~terro.:;n ol e~hl.ch it -.·.-n::; po~siblc t"J n:.~ccrtulu '.;i}c t•atr. of opcr.ch nnd 1 oqunc1 clur lnc nn:r pcridd. t~· . .by Rn tc of speech and loquncl ty were·· oaccrt.ntnna counti~ the nW'i11Jer of words uttorecl by tho :m1:joct in two minutes O"..lt of every five durin.: the 1ntcrro.-:;r.t1on nnd by .• rnoacurlnz the length of tlr.io he tnlkcu in nny t\tO r.dnuto • pftriod. By plott11lb tho3o findinGs it possible to wa~ to present graphically the effect of T.D on rate and loquacity. ____. ._:t -4- ' PJ,E.T II Pnychocalvnnometor About one-ho.lf the sub joct~ wc:·o oxlimlncd by menno of the psychor:nlvanortC'tcr to P~plorc tlw po:.;sl'bllltics of U!1in: th(• ter.lmiquc l'or uncove:.·in,e lll.!'or, '.ut;,lon u~t ·eo.sil:,· eliciteu. ThA technique C!ltpl;:,ycd was us:.;out.iull:r ·~hnt r:io.de us~ of. !.n "lio clet-:-ction" r..nrJ v1lll be doocrlbou 'Lol')w • '·- • 01. to .U2 c9 l.r:r r~outh, 'IH~1·o nt1l:linl~te,·0tl to tho. ~·ort:,· ' ut~iutU1t.3 of .00 cc were toxic in r:to:.:i.; o.;. ~.l: lac.1l·;lc1i.t~l; 'to • 01 cr; ty l'li.. n ttll v;n~ <l.i~ c

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