Doc 0000146168

( ( 31 July 1975 SUBJECT: _]File RevieN .. J~. The imdersigned has reviel'led three folders labeled_ _ J These folders contain reports and miscellaneous correspondence pertaining to a classified contract bet\·:een the Agency and the 1\ational Institute of ~rental Health, U.S. Public Health Service. Under t.U.s contract the NI~H conducted tests of various hallucinogenic dntgs incl~~­ ing LSD. The stated purpose of the eJ~.-periments l-ias "to find synthetic analgesic and antitussive drugs which are as safe or safer than codeine." The file indicates this 1-:ork \·:as initiated by the Department of Defense prior to 1951 and continued ~~der Agency sponsorship from 1951-52 thro~gh 1962. Ftmds were W tially transferred through the Office of No:r.-al Research and presomably this mechanism \'las used throughout the contractin_s pericd. Ftmds involved varied ben..-een · · · - -- ~ -·-.... \ 2. Actual testing of the drugs 1..-as perfonned by N"DiH perso:mel at the _l'{ational. Institute of :Mental Health, Addiction Research Center, Lexington, Kentud.-y. .According to docu:nents in the file, testing \·:as acco;:;;>lishecl on animals and human volt.mteers. The file indicates that the htr.'.an voll.mteers 1vere patients at the facility in Lexington. The Agency project renelial states that the tests "are accepted·as standards for legal acti:;,n by the Committee on Drug Addict-ion and Narcotics, National Research Cotl:').cil". There is no indication in the files that testing \'las done on l.ml\itting hu:::ms. 3. The file does not indicate 1-;hat use the Agencr made of the reS"..tlts of the project. A report entitled "Final Progress REport" is contained in file folder #3. This report summarizes the results of the project through 1962 and states that the project 1d.ll continue 1dth NDIH financing. The report states that the goals of the project 1\ere realized. Among-the results \~·ere the discovery of t\-:o useful analgesics (Darvon ai;d \·ersidj-:le) and a11 antitussive (Ro:nilar) as well as a nu'Ilber of other drugs \'lhich :::ay offer a substitute for codeine. · · I "!"" The image displays a stylized graphic of a bank vault door on the left side, with a glowing blue light emanating from behind it. The text on the right explains that the document was obtained from "The Black Vault," an online database of declassified government documents, specifically from the MKULTRA/Mind Control Collection. The text further states that this collection houses over 20,000 declassified pages from the Central Intelligence Agency (CIA) and provides a URL for downloading the entire collection. There are no photographs, handwritten annotations, official stamps, forms, diagrams, tables, or evidence of experimental procedures visible in this image. The visual elements are purely decorative and textual, serving to frame and contextualize the information about the document's source. The document is a typed memorandum dated July 31, 1975, with a handwritten annotation "416" at the top right and a circled "4" to the right of the date. The memorandum discusses a file review of three folders related to a classified contract concerning hallucinogenic drugs. The content includes numbered paragraphs detailing the contract, testing procedures performed on animals and human volunteers, and the project's reported outcomes. There are no photographs, diagrams, stamps, forms, tables, redactions, or visual evidence of experimental procedures.